Preface. Chapter 1: Open computing Grid for molecular sciences (M. Romberg, E. Benfenati, and W. Dubitzky). Chapter 2: Designing high-performance concurrent strategies for biological sequence alignment problems on networked computing platforms (B. Veeravalli). Chapter 3: Optimized cluster-enabled HMMER searches (J. P. Walters, J. Landman, and V. Chaudhary). Chapter 4: Expanding the rich of Grid computing: combining Globus and BOINC based systems (D. S. Myers, A. L. Bazinet, and M. P. Cummings). Chapter 5: Hierarchical Grid computing for high performance bioinformatics (B. Schmidt, C.X. Chen and W. Liu). Chapter 6:Multiple sequence alignment and phylogenetic inference (D. Trystram, and J. Zola). Chapter 7: Data syndication techniques for bioinformatics applications (C. Wang, A. Y. Zomaya, and B. B. Zhou). Chapter 8: Conformational sampling and docking on Grids (A. Tantar, N. Melab, and E-G. Talbi). Chapter 9: Deployment of Grid life sciences applications (V. Breton,
N. Jacq, V. Kasam, and J. Salzemann). Chapter 10: Grid-based interactive decision support in biomedicine (A. Tirado-Ramos, P. M. A. Sloot, and M. Bubak). Chapter 11: Database-driven grid computing and distributed web applications: a comparison (H. De Sterck, A.Papo, C. Zhang, M. Hamady, and R. Knight). Chapter 12: A semantic mediation architecture for a clinical Data Grid (K. Kumpf, A. Wohrer, S. Benkner, G. Engelbrecht, and Jochen Fingberg). Chapter 13: Bioinformatics applications in Grid computing environments (A. Boukerche, A. C. Magalhaes and Alves De Melo). Chapter 14: Recent advances in solving the protein threading problem (R. Andonov, G. Collet, J-F. Gibrat, A. Marin, V. Poirriez, and N. Yanev). Chapter 15: DNA fragment assembly using Grid systems (A. J. Nebro, G. Luque, and E. Alba). Chapter 16: Seeing is knowing: Visualization of parameter-parameter dependencies in biomedical network models (A. Konagaya, R. Azuma, R. Umetsu, S. Ohki, F. Konishi, K. Matsumura, and S. Yoshikawa).