Skip to main content

Grignard Reagents: New Developments



Grignard Reagents: New Developments

H. G. Richey (Editor)

ISBN: 978-0-471-99908-9 January 1999 434 Pages


The Grignard reagent is one of the most useful and versatile reagents known to the organic chemist and 100 years after its discovery, this book presents authoritative perspectives on the significant developments taking place using Grignard Reagents and related organomagnesium compounds.

This volume focuses on a dozen areas of organomagnesium chemistry, including:

* New reactions of Grignard Reagents

* Stereoselective Reactions of Organomagnesium Compounds

* Mechanistic Features of Organomagnesium Compounds

* Industrial Applications and Strategy

* Unusual Organomagnesium Compounds

* Structures of Organomagnesium Solids and Solutions

The book will prove of great interest to academic and industrial chemists active in organometallic chemistry of main group metals, organic syntheses, reaction mechanisms and structural organic chemistry.
New Reactions of Grignard Reagents.

Stereoselective Reactions of Organomagnesium Compounds.

Mechanistic Features of Organomagnesium Compounds.

Industrial Applications and Strategy.

Unusual Organomagnesium Compounds.

Structures of Organomagnesium Solids and Solutions.
"Aimed at a broad spectrum of both academic and industrial readers, this excellent and well presented collection of reviews provides a wealth of new insights into an old topic", Christopher Glidewell, , Chemistry and Industry#"Grignard Reagents - Industrial Applications and Strategy is a superb review by F.R. Busch and D.M. de Antonis of the practices used at Pfizer to safely scale-up Grignard Reactions. It includes such topics as reactor configuration, choice of solvent, process hazards, heating and cooling fluids, reaction initiation as well as some industrial examples. The book is worth reading for this chapter alone.", Dr Trevor Laird, , Organic Process Research and Development#