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Haematology at a Glance, 4th Edition

Atul B. Mehta, A. Victor Hoffbrand

ISBN: 978-1-119-96922-8 April 2014 Wiley-Blackwell 136 Pages


Following the familiar, easy-to-use at a Glance format, Haematology at a Glance, Fourth Edition is a broad and accessible introduction to the study of blood. Fully revised and updated to reflect advances in the field and in clinical practice, this new edition covers essential knowledge, from basic hematological physiology to blood disorders and their diagnosis and treatment.

This new edition of Haematology at a Glance:

• Features expanded sections on the underlying mechanisms, diagnostic techniques and management of the malignant haematological diseases. Also incorporates recent advances in knowledge of thrombosis and the newer oral anticoagulants
• Contains the very latest clinical treatments
• Includes updated illustrations and clinical photographs to illustrate concepts and aid understanding
• Features extensive online self-assessment at

This book is an invaluable resource for medical students and health professionals wanting to consolidate and expand their knowledge of haematology.

Preface to the fourth edition 6

Preface to the first edition 6

Glossary 7

Normal values 8

About the companion website 9

Part 1 Basic physiology and practice

1 Haemopoiesis: physiology and pathology 10

2 Normal blood cells I: red cells 14

3 Normal blood cells II: granulocytes, monocytes and the reticuloendothelial system 18

4 Normal blood cells III: lymphocytes 20

5 Lymph nodes, the lymphatic system and the spleen 23

6 Clinical assessment 24

7 Laboratory assessment 26

Part 2 Red cell disorders

8 General aspects of anaemia 30

9 Iron I: physiology and deficiency 33

10 Iron II: overload and sideroblastic anaemia 36

11 Megaloblastic anaemia I: vitamin B12 (B12) and folate deficiency – biochemical basis, causes 38

12 Megaloblastic anaemia II: clinical features, treatment and other macrocytic anaemias 40

13 Haemolytic anaemias I: general 42

14 Haemolytic anaemias II: inherited membrane and enzyme defects 44

15 Haemolytic anaemias III: acquired 46

16 Haemolytic anaemias IV: genetic defects of haemoglobin – thalassaemia 48

17 Haemolytic anaemias V: genetic defects of haemoglobin – sickle cell disease 52

Part 3 Benign disorders of white cells

18 Benign disorders of white cells I: granulocytes, monocytes, macrophages 54

19 Benign disorders of white cells II: lymphocytes, lymph nodes, spleen, HIV 56

Part 4 Haematological malignancies

20 Introduction to Haematological malignancy: basic mechanisms 58

21 General aspects of treatment 61

22 Acute leukaemia I: classifi cation and diagnosis 64

23 Acute leukaemia II: treatment and prognosis 68

24 Chronic Myeloid Leukaemia (BCR-ABL1 positive) 70

25 Myelodysplasia (myelodysplastic syndromes) 72

26 Myeloproliferative disorders I: introduction 74

27 Myeloproliferative disorders II: polycythaemia rubra vera 76

28 Myeloproliferative disorders III: essential thrombocythaemia, primary myelofi brosis and systemic mastocytosis 78

29 Chronic lymphocytic leukaemia 80

30 Multiple myeloma and plasma cell disorders 83

31 Lymphoma I: introduction 86

32 Lymphoma II: Hodgkin lymphoma 88

33 Lymphoma III: non-Hodgkin lymphoma – aetiology and classification 90

34 Lymphoma IV: clinical and laboratory features of more common subtypes 92

35 Lymphoma V: treatment and prognosis 94

Part 5 Treatment and procedures

36 Bone marrow failure 96

37 Haematological effects of drugs 98

38 Stem cell transplantation 100

Part 6 Haemostasis

39 Normal haemostasis I: vessel wall and platelets 102

40 Normal haemostasis II: coagulation factors and fi brinolysis 104

41 Disorders of haemostasis I: vessel wall and platelets 106

42 Disorders of haemostasis II: inherited disorders of coagulation 108

43 Disorders of haemostasis III: acquired disorders of coagulation 110

44 Thrombosis and anti-thrombotic therapy 112

45 Anticoagulation 115

Part 7 Haematological aspects of tropical disease

46 Haematological aspects of tropical diseases 118

47 Haematology of pregnancy and infancy 120

Part 8 Blood transfusion

48 Blood transfusion I 122

49 Blood transfusion II 124

Appendix: cluster of differentiation nomenclature system 127

Index 129

“This book is an invaluable resource for medical students and health professionals wanting to consolidate and expand their knowledge of haematology.”  (Kingbook73's Medical Ebook and Video Collection, 26 August 2014)

Haematology at a Glance Companion website  features extensive interactive self-assessment.