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Handbook of Fluorous Chemistry

Handbook of Fluorous Chemistry

John A. Gladysz (Editor), Dennis P. Curran (Editor), István T. Horváth (Editor)

ISBN: 978-3-527-60449-4

Mar 2006

624 pages



Edited by the leading experts John Gladysz, Dennis Curran, and István Horváth, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation of contributions, written by the world's top authors, provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory. In addition, experts will also find a wealth of important information concisely contained in one ready reference. The result is an indispensable resource for everyone currently working or intending to work in this field.

1. Fluorous Chemistry: Scope and Definition (I. Horváth, et al.).

2. A Personal View of the History of Fluorous Chemistry (I. Horváth).

3. Fluorous Solvents and Related Media (J. Gladysz & C. Emnet).

4. Strategies for the Recovery of Fluorous Catalysts and Reagents: Design and Evaluation (J. Gladysz & R. Corréa de Costa).

5. Ponytails: Structural and Electronic Considerations (J. Gladysz).

6. Partition Coefficients Involving Fluorous Solvents (J. Gladysz, et al.).

7. Separations with Fluorous Silica Gel and Related Materials (D. Curran).

8. Light Fluorous Chemistry—A User´s Guide (D. Curran).

9. Getting Started in Synthesis: A Tabular Guide to Selected Monofunctional Fluorous Compounds (J. Rábai).

10. Highlights of Applications in Synthesis and Catalysis.

11. Preparations.

12. Applications of Fluorous Compounds in Materials Chemistry.

13. Fluorous Materials for Biomedical Uses (J. Riess).

14. Fun and Games with Fluorous Chemistry (J. Rábai).


"…very useful for analytical chemists as well as for researchers and students needing to analyze the various components to which ion chromatography is applicable." (American Reference Books Annual, 2006)

"…essential reading for all individual intending to work in this field or a valuable desk reference for experienced chemists." (E-STREAMS, August 2005)

"..not of the first handbooks focused on the task of demystifying fluorous chemistry, a way to encourage the laboratory chemist to be creative and embark on his own investigation." (Electric Review, October/ November 2004)

"... this handbook provides all the answers needed for working with the diverse and fascinating families of fluorous molecules." (Process, 4 October 2004, Vol. 7)