Skip to main content

Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues

Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues

Christoph W. Sensen (Editor)

ISBN: 978-3-527-61973-3

Jan 2008, Wiley-Blackwell

646 pages

Select type: O-Book

Description

In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the development of new active substances, agri-food and environmental genomics.
There then follows an overview of current topics central to DNA technologies, proteomics, metabolomics and bioinformatics, including such hot topics as DNA chip fabrication, yeast two hybrid analysis, tools for gene expression studies, metabolic networks and systems biology.
The whole is rounded off by four chapters on the ethical, legal and social aspects of this sensitive topic.
I KEY ORGANISMS
Genome Projects on Model Organisms
Environmental Genomics: A Novel Tool for Study of Uncultivated Microorganisms
Applications of Genomics in Plant Biology
II GENOMIC AND PROTEOMIC TECHNOLOGIES
Human Genetic Diseases
Genomic Mapping and Positional Cloning, with Emphasis on Plant Science
DNA Sequencing Technology
Proteomics and Mass Spectrometry for the Biological Researcher
Proteome Analysis by Capillary Electrophoresis
A DNA Microarray Fabrication Strategy for Research Laboratories
Principles of Application of DNA Microarrays
Yeast Two-hybrid Technologies
Structural Genomics
III BIOINFORMATICS
Bioinformatics Tools for DNA Technology
Software Tools for Proteomics Technologies
Applied Bioinformatics for Drug Discovery and Development
Genome Data Representation Through Images: The MAGPIE/Bluejay System
Bioinformatics Tools for Gene-expression Studies
Protein Interaction Databases
Bioinformatics Approaches for Metabolic Pathways
Systems Biology
IV ETHICAL, LEGAL AND SOCIAL ISSUES
Ethical Aspects of Genome Research and Banking
Biobanks and the Challenges of Commercialization
The (Im)perfect Human -
His Own Creator? Bioethics and Genetics at the Beginning of Life
V OUTLOOK
The Future of Large-Scale Life Science Research
"This set should be purchased by university libraries interested in genome research and its implications."
American Reference Books Annual

"... advanced scientists in genome research should find this handbook's chapters, which are ... through, to be of value."
CHOICE