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Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis

Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis

Shigeo Nishimura

ISBN: 978-0-471-39698-7

Apr 2001

720 pages

Select type: Hardcover

In Stock



The most comprehensive reference in the field, Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis provides synthetic chemists and chemical engineers in fine chemicals and pharmaceuticals with detailed experimental guidelines for heterogeneous catalytic hydrogenation. Organized by functional groups for ready reference and featuring detailed examples of hundreds of reactions, this handbook covers hydrogenations of alkenes, alkynes, aldehydes and ketones, nitriles, imines, nitro and nitroso compounds, carboxylic acids and esters, and aromatic and heterocyclic compounds. In addition, coverage includes the preparation of amines by reductive alkylation and the hydrogenolysis of a variety of compounds. Examples of hydrogenation of functional groups and reaction pathways are illustrated with numerous equations and schemes.

Practitioners will appreciate the plenitude of experimental details given for most of the reactions selected, including amounts of reagents and catalysts, reaction temperatures, hydrogen pressures, and reaction times. They will also find helpful the more than one hundred tables included throughout the book detailing the effects of key factors governing rate and selectivity, such as compound structure, the nature of catalysts and supports, and the nature of solvents. Researchers will benefit from the introductory chapters covering an array of hydrogenation catalysts, including nickel, cobalt, copper, iron, platinum group metals, rhenium, and other oxide and sulfide catalysts, as well as reactors and reaction conditions.


Hydrogenation Catalysts.

Reactors and Reaction Conditions.

Hydrogenation of Alkenes.

Hydrogenation of Alkynes.

Hydrogenation of Aldehydes and Ketones.

Preparation of Amines by Reductive Alkylation.

Hydrogenation of Nitriles.

Hydrogenation of Imines, Oximes, and Related Compounds.

Hydrogenation of Nitro, Nitroso, and Related Compounds.

Hydrogenation of Carboxylic Acids, Esters, and Related Compounds.

Hydrogenation of Aromatic Compounds.

Hydrogenation of Heterocyclic Aromatic Compounds.


General Bibliography.

Author Index.

Subject Index.
""Chemists will find this a useful guide and it should be in all organic chemistry libraries."" (Organic Process Research & Development Journal)

""...this book is easy to use to find information adds to a useful armoury for dealing with most is therefore good value..."" (Platinum Metals Review, Vol. 46, No. 2, April 2002)

""this book is easy to use to find information quickly"" (Platinum Metals Review, April 2002)

""...a welcome and valuable day-to-day manual..."" (Synthesis, No.9, 2002)