The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past ten years. In particular the modeling advent of cheap, high-volume DNA sequencing along with other advances have revolutionised the field. As a consequence the 4th edition of the handbook contains a much expanded section on these areas, along with several new chapters which focus on statistical aspects of new sequencing technologies and their implications, particularly sequence-based functional assays, leading to more aspects of genetic regulation and pathways/networks.
As with the 3rd Edition, the Handbook also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research.