DescriptionReviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.
Control of in Vivo IgE Production in the Mouse by Interleukin 4 (F. Finkelman, et al.).
Different Mast Cell Mediators Produced by Different Mast Cell Phenotypes (M. Gurish & K. Austen).
Mast Cells: Immunologically Specific Effectors and Potential Sources of Multiple Cytokines During IgE-Dependent Responses (S. Galli, et al.).
The Receptor with High Affinity for IgE (H. Metzger, et al.).
Calcium: An Important Second Messenger in Mast Cells (C. Fewtrell, et al.).
Low Affinity IgE Receptors: Regulation and Functional Roles in Cell Activation (J. Yodoi, et al.).
IgE and Inflammatory Cells (A. Capron, et al.).
Molecular Genetics of Human Responsiveness to Allergens (D. Marsh, et al.).
Influence of Environmental Factors on IgE Production (S. Takafuji, et al.).
Epidemiology of the Allergic Response (K. Turner).
Conventional and New Approaches to Hyposensitization (A. de Weck).
Index of Contributors.