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In Vivo Glucose Sensing

David D. Cunningham (Editor), Julie A. Stenken (Editor)

ISBN: 978-0-470-11296-0 December 2009 476 Pages


In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.


Chapter 1. Introduction to the Glucose Sensing Problem (George S. Wilson and Yanana Zhang).

Chapter 2. The Macrophage in Wound Healing Surrounding Implanted Devices (Marisha L. Godek and David W. Grainger).

Chapter 3. Strategies to Overcome Biological Barriers to Biosensing (W. Kenneth Ward and Heather M. Duman).

Chapter 4. A Window to Observe the Foreign Body Reaction to Glucose Sensors (Milan T. Makale and Jared B. Goor).

Chapter 5. Commercially Available Continuous Glucose Monitoring Systems (Timothy Henning).

Chapter 6. Membrane-Based Separations Applied to In Vivo Glucose Sensing-Microdialysis and Ultrafiltration Sampling (Julie A. Stenken).

Chapter 7. Transdermal Microfluidic Continuous Monitoring Systemsn (David D. Cunningham).

Chapter 8. Redundant Arrays and Next-Generation Sensors (Becky L. Clark and Michael V. Pishko).

Chapter 9. Nitric Oxide-Releasing Subcutaneous Glucose Sensors (Heather S. Paul and Mark H. Schoenfisch).

Chapter 10: Fluorescence-Based Glucose Sensors (Mike McShane and Erich Stein).

Chapter 11. The Use of Single-Walled Carbon Nanotubes for Optical Glucose Detection (Paul W. Barone and Michael S. Strano).

Chapter 12. Introduction to Spectroscopy for Noninvasive Glucose Sensing (Wei-Chuan Shih, Kate L. Bechtel, Michael S. Feld, Mark A. Arnold and Gary W. Small). 

Chapter 13. Near-Infrared Spectroscopy for Noninvasive Glucose Sensing (Mark A. Arnold, Jonathon T. Olesberg and Gary W. Small). 

Chapter 14. Noninvasive Glucose Sensing with Raman Spectroscopy (Wei-Chuan Shih, Kate L. Bechtel and Michael S. Feld).

Chapter 15. Surface-Enhanced Raman Spectroscopy for Glucose Sensing (Nilam C. Shah, Jonathan M. Yuen Olga Lyandres, Matthew R. Glucksberg, Joseph T. Walsh and Richard P. Van Duyne).


"The book chapters are written by well-known experts in the field. The book can be considered as an important contribution to the literature on implantable and transdermal sensors and provides a description of the latest technology and a practically oriented approach to in vivo glucose sensing." (Anal Bioanal Chem, 2010)