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Inductively Coupled Plasma Mass Spectrometry Handbook

Inductively Coupled Plasma Mass Spectrometry Handbook

Simon Nelms (Editor)

ISBN: 978-1-444-30546-3

Mar 2009, Wiley-Blackwell

504 pages

Select type: O-Book


Since the first reported linking of an Inductively Coupled Plasma (ICP) ion source with a mass spectrometer (MS) in 1983, the instrumentation and analytical techniques have been developed to a point where the technology can deliver detection limits of one part in 10^15. With this level of detection, ICP-MS is an invaluable tool in a huge range of applications. Development of the technology continues, for example with the application of lasers to allow direct analysis of solid samples and with linkages to liquid chromatography apparatus for elemental speciation studies, further opening up the scope for this highly sensitive analytical technique.Despite widespread interest and usage, little has been written to describe the analytical techniques and instrumentation in a format accessible to both new and experienced users of the technique. The aim of this book is, therefore, to provide a thorough description of ICP-MS instrumentation and techniques, giving the reader sufficient knowledge to approach the technique with confidence.
Chapter 1: Plasma generation, ion sampling and focusing.

Chapter 2: Mass spectrometers.

Chapter 3: Ion detection, Data Acquisition and Handling.

Chapter 4: Calibration strategies and quality assurance.

Chapter 5: Liquid sample introduction: Fundamentals and applications of flow injection and electrothermal vaporisation for ICP-MS.

Chapter 6: Laser ablation.

Chapter 7. Speciation Analysis.

Chapter 8: Collision and reaction cells.

Chapter 9: ICP-MS Applications.

"It is well worth the investment in that it will make a good reference book for newcomers and experienced users alike." (J Am Soc Mass Spectrom, 2007)

"This handbook is written for both experienced analysts and for those which are newcomers in the field of ICP MS. This book provides a thorough description of ICP MS instrumentation and techniques, giving the reader sufficient knowledge to approach the technique with confidence"..."[T]his book forms an excellent and very meticulous reference text."..."In conclusion, this book provides a detailed description of current instrumentation and its capabilities, and analytical considerations like interferences and key application of ICP MS. The information herein is very valuable to scientists using ICP MS, as well as those seeking further improvements in the performance. This book answers the actual needs, and therefore is a very valuable contribution."

Chemical Analysis (Warsaw) Vol.51 Issue.327 (2006)


"We believe that this monograph will be a valuable handbook for a wide circle of experts working with ICL MS instruments and those analysts who are going to learn more about the most powerful method of instrumental elemental analysis."

Journal of Analytical Chemistry Vol. 62 No. 2 (2007)

* Detailed descriptions of both instrumentation and analytical techniques allows new users to build up a framework of understanding quickly and cheaply

* Key reference source and entry to the literature so the reader does not have to engage in expensive and time consuming literature searching to obtain critical technique based information

* Critically evaluates the most recent developments providing experienced users with a convenient review of the trends in analytical capabilities