1 Lead Discovery: The Process (William F. Michne).
2 High Throughput Screening Approach to Lead Discovery (Zoran Rankovic, Craig Jamieson, and Richard Morphy).
3 In Silico Screening (Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath).
4 Fragment-Based Lead Discovery (Jeffrey S. Albert).
5 Design of Multitarget Ligands (Richard Morphy and Zoran Rankovic).
6 De novo Drug Design (Gisbert Schneider, Markus Hartenfeller, and Ewgenij Proschak).
7 Role of Natural Products in Drug Discovery (Hugo Lachance, Stefan Wetzel, and Herbert Waldmann).
8 Early Screening for ADMET Properties (Dennis A. Smith).
9 Role of Chemistry in Lead Discovery (Roland E. Dolle and Karin Worm).
"This volume is recommended to chemists and biologists who wish to learn about the practice of high throughput screening and about the concepts involved in making the method a successful route to drug discovery." (Journal of Medicinal Chemistry, 2010)"Each chapter provides a comprehensive overview of one aspect of the lead generation process. To get more indepth knowledge, extensive references including recent publications are given." (ChemMedChem, 2010)