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Medicinal Natural Products: A Biosynthetic Approach, 2nd Edition

Medicinal Natural Products: A Biosynthetic Approach, 2nd Edition

Paul M. Dewick

ISBN: 978-0-470-84627-8

Nov 2001

520 pages

Select type: O-Book

Description

Medicinal Natural Products, Second Edition is a comprehensive guide providing information on all classes of natural products in medicine. It builds upon fundamental chemical principles and demonstrates a unique integration of plant, microbial and animal natural products in one volume. The text guides the reader through a wealth of diverse natural metabolites used in medicine with sources, production methods, use as drugs and modes of action all extensively covered. Taking a chemistry based approach it combines traditional pharmacognosy with medicinal chemistry. The structure is user-friendly and includes the acclaimed grey boxes on groups of products and detailed mechanistic explanations.
* Adopts a novel biosynthetic theme rather than a traditional descriptive approach
* Includes extensive further reading at the end of the chapter
* Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products
* Includes the latest developments in the field
* New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
* User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations
About this book and how to use it

Secondary metabolism: The building blocks and construction mechanisms

The acetate pathway: Fatty acids and polyketides

The shikimate pathway: Aromatic amino acids and phenylpropanoids

The mevalonate and deoxyxylulose phosphate pathways: Terpenoids and Steroids:

Alkaloids

Peptides, proteins and other amino acid derivatives

Carbohydrates

Index
Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products

Includes the latest developments in the field

New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
"...an excellent and accurate reference source..." (Journal of Ethnopharmacology, No.81, 2002) 

"...I shall certainly use this text and I shall value it..." (Natural Products Report, Vol.19, No.3, 2002)

"The price of the paper-back will allow not only to have it in the library but also on the personal bookshelf." (Journal of Plant PhysiologyNo.159, 2002)

  • Comprehensive coverage of plant, microbial and animal products
  • User-friendly structure - including the acclaimed grey boxes on groups of products and detailed mechanistic explanations
  • Novel biosynthetic theme, not a traditional descriptive approach
  • Extensive further reading at the end of each chapter