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Metal-catalyzed Cross-coupling Reactions

Metal-catalyzed Cross-coupling Reactions

François Diederich (Editor), Peter J. Stang (Editor)

ISBN: 978-3-527-61222-2

Nov 2007

540 pages

Select type: O-Book


Carbon-carbon bond forming reactions are arguably the most important processes in chemistry, as they represent key steps in the building of complex molecules from simple precursors. Among these reactions, metal-catalyzed cross-coupling reactions are extensively employed in a wide range of areas of preparative organic chemistry, ranging from the synthesis of complex natural products, to supramolecular chemistry, and materials science.
In this work, a dozen internationally renowned experts and leaders in the field bring the reader up to date by documenting and critically analyzing current developments and uses of metal-catalyzed cross-coupling reactions. A particularly attractive and useful feature, that enhances the practical value of this monograph, is the inclusion of key synthetic protocols, in experimental format, chosen for broad utility and application.
This practice-oriented book can offer the practitioner short cuts to ensure they remain up-to-date with the latest developments.
Pd-Catalyzed 1,4-Additions
Organosilicon Compounds in Cross Coupling Reactions
Organozinc and Copper Reagents
Heck-Coupling Reactions
Organotin Reagents in Cross Coupling
Organozinc, Organozinconium, Al and Mg Reagents
Carbometalation Reactions
Cross-Coupling Reactions in Natural Product Synthesis
Ortho Metalation Cross Coupling Strategies
Cross-Coupling Reactions to sp-C-atoms
Pd-Catalyzed Cross Coupling Reactions of Organoboron Compounds
Palladium Catalyzed Carbonylation
This book presents in eleven chapters a broad and well-balanced review of metal-catalyzed cross-coupling reactions. The contributing authors are some of the leaders in the field, and indeed their articles contain a wealth of useful and up-to-date material.
(Angewandte Chemie)