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Microfluidics and Nanofluidics: Theory and Selected Applications

Microfluidics and Nanofluidics: Theory and Selected Applications

Clement Kleinstreuer

ISBN: 978-1-118-74989-0

Nov 2013

456 pages

Description

Fluidics originated as the description of pneumatic and hydraulic control systems, where fluids were employed (instead of electric currents) for signal transfer and processing. Microfluidics and Nanofluidics: Theory and Selected Applications offers an accessible, broad-based coverage of the basics through advanced applications of microfluidics and nanofluidics. It is essential reading for upper-level undergraduates and graduate students in engineering and professionals in industry.

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Preface xv

Part A: A REVIEW OF ESSENTIALS IN MACROFLUIDICS 1

CHAPTER 1 Theory 3

1.1 Introduction and Overview 3

1.2 Definitions and Concepts 8

1.3 Conservation Laws 23

1.4 Homework Assignments 74

CHAPTER 2 Applications 79

2.1 Internal Fluid Flow 79

2.2 Porous Medium Flow 108

2.3 Mixture Flows 118

2.4 Heat Transfer 151

2.5 Convection-Diffusion Mass Transfer 162

2.6 Homework Assignments 176

References (Part A) 186

Part B: MICROFLUIDICS 189

CHAPTER 3 Microchannel Flow Theory 191

3.1 Introduction 191

3.2 Basic Concepts and Limitations 195

3.3 Homework Assignments 251

CHAPTER 4 Applications in Microfluidics 255

4.1 Introduction 255

4.2 Micropumps and Microchannel Flow 256

4.3 Micromixing 280

4.4 Laboratory-on-a-Chip Devices 284

4.5 Homework Assignments and Course Projects 288

References (Part B) 290

Part C: NANOFLUIDICS 293

CHAPTER 5 Fluid Flow and Nanofluid Flow in Nanoconduits 295

5.1 Introduction 295

5.2 Liquid Flow in Nanoconduits 303

5.3 Rarefied Gas Flow in Nanochannels 328

5.4 Homework Assignments and Course Projects 335

CHAPTER 6 Applications in Nanofluidics 339

6.1 Introduction 339

6.2 Nanoparticle Fabrication 340

6.3 Forced Convection Cooling with Nanofluids 342

6.4 Nanodrug Delivery 351

6.5 Homework Assignments and Course Projects 356

References (Part C) 358

Part D: COMPUTER SIMULATIONS OF FLUID-PARTICLE MIXTURE FLOWS 361

CHAPTER 7 Modeling and Simulation Aspects 363

7.1 Introduction 363

7.2 Mathematical Modeling 365

7.3 Computer Simulation 367

CHAPTER 8 Computational Case Studies 375

8.1 Introduction 375

8.2 Model Validation and Physical Insight 376

8.3 Solid Tumor Targeting with Microspheres 386

8.4 Homework Assignments and Course Projects 390

References (Part D) 393

APPENDICES 395

APPENDIX A 397

A.1 Tensor Calculus 397

A.2 Differentiation 403

A.3 Integral Transformations 407

A.4 Ordinary Differential Equations 411

A.5 Transport Equations (Continuity, Momentum, and Heat Transfer) 415

APPENDIX B 420

B.1 Conversion Factors 420

B.2 Properties 423

B.3 Drag Coefficient: (A) Smooth Sphere and (B) An Infinite Cylinder as a Function of Reynolds Number 427

B.4 Moody Chart 428

References (Appendices) 429

INDEX 431