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Modern Amination Methods

Modern Amination Methods

Alfredo Ricci

ISBN: 978-3-527-61319-9

Jul 2008

285 pages

Select type: E-Book



Organic compounds containing amino groups are at the center of modern organic chemistry, and are widely used in the pharmaceutical industry, crop protection, natural product chemistry, and in advanced materials. Modern methods for the introduction of the amino group are therefore of major importance to synthetic chemists and product developers.

Over the last decade, many methods have been developed to generate new C-N bonds. At the same time, the pharmaceutical and chemical industry was rapidly moving away from the development of racemic compounds to the direct synthesis of enantiomerically pure materials. The articles of this book, written by internationally recognized experts, thus focus on asymmetric synthesis.

The most recent catalytic amination methods have particularly revolutionized the chemistry of amino compounds - and you find them all in this first comprehensive overview.
Design and preparation of (salen)Mn complexes and their use as aminating agents in the synthesis of aminoketones and of aminosaccarides by reaction with olefins
Stereoselctive electrophilic amination with sulfonyl carbamates and azodicarboxylates
Transition Metal-Catalysed Amination to form Aromatic Carbon-Nitrogen Bonds
Glycosylamines as the Stereodifferentiating Tools in Enantioselective Synthesis of Amino Acids and N-Heterocycles
Allylic Amination Reactions
Chiral nitrido-MN complexes and their use in asymmetric synthesis of aziridines
Asymmetric electrophilic amination
""...the reviews are of a uniformly high standard and the book amply succeeds in its aim of providing a valuable overview of the field that can be recommended to all synthetic chemists.""
Organic Process Research and Development Jnl.