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Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins

Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins

Rainer Fischer (Editor), Stefan Schillberg (Editor)

ISBN: 978-3-527-60581-1

Mar 2006, Wiley-Blackwell

338 pages

Select type: E-Book



Here, authors from academia and industry provide an exciting overview of current production technologies and the fascinating possibilities for future applications. Topics include chloroplast-derived antibodies, biopharmaceuticals and edible vaccines, production of antibodies in plants and plant cell suspension cultures, production of spider silk proteins in plants, and glycosylation of plant produced proteins. The whole is rounded off by chapters on the demands and expectations made on molecular farming by pharmaceutical corporations and the choice of crop species in improving recombinant protein levels.
Of interest to biotechnologists, gene technologists, molecular biologists and protein biochemists in university as well as the biotechnological and pharmaceutical industries.

Perennial plants as a production system for pharmaceuticals
Foreign protein expression using hairy roots and plant suspension cultures
Production of recombinant proteins in germinating seeds
Viral expression vectors
Field trials
Chloroplast derived antibodies, biopharmaceuticals and edible vaccines
sIgA production in plants
Antibodies in plants and plant cell suspension cultures

Production of spider silk proteins in plants
Glycosylation of plant produced proteins
The precautionary approach to tackle the wicked problems
Requirements and expectations of Molecular Farming from the view of big pharma
Choice of crop species and improving recombinant protein levels
Gene farming in pea under field conditions: Seed specific synthesis of a bacterial exoenzyme
Bioforum, Oktober 2004

""Die Zusammenstellung der vorliegenden Beiträge liefert eine sehr gute und interessante Übersicht über die derzeitigen Arbeiten zum Molecular Farming.""
Pharmazie in unserer Zeit