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Molecular and Genetic Analysis of Human Traits

Molecular and Genetic Analysis of Human Traits

Gustavo Maroni (Editor)

ISBN: 978-0-470-75980-6 April 2008 Wiley-Blackwell 288 Pages

 E-Book

$95.99

Description

Molecular and Genetic Analysis of Human Traits will address the science student human genetics market. Although incorporating two basic themes: how do we establish that a trait is hereditary, and how is the human genome organized, it will also address relevant clinical examples and key related ethical issues. New attractive features have been added, including a chapter project, and end of chapter exercises which rely on real data.

  • Each chapter includes end of chapter exercises, and references.
  • In-text examples and internet references are cited.
  • Most figures will be 2 color, with some 4 color inserts.
Preface.

The Inheritance of Simple Mendelian Traits in Humans.

Hereditary Traits That Do Not Show a Simple Mendelian Pattern.

Genome Organization I.

Genome Organization II.

Chromosomes and Karyotypes.

How Mutant Alleles Affect the Phenotype.

Mutations: Damage and Repair of DNA.

Cancer: A Genetic Disease.

Genetic Counseling.

Appendix.

Index.

"I will be looking for a new general text that does a good job presenting the basics - the clinical texts will not do that for me, nor will the texts that present human genetics as problems to be solved, one disease at a time. I would be interested in considering this text should it be published." Joan Rutila, Brandeis University <!--end-->

"I DO agree with the author's two lines of thought, I think they are very good approaches and in texts that I have reviewed, I have not found such an organisation. If I were teaching a majors course with a lecture format, I would like such an approach." Rita Calvo, Cornell University

Praise from reviews:

The author has clearly done a great deal of research across a broad spectrum of genetic studies in finding the examples that he has chosen to illustrate concepts. I would like to adopt this text for my class, and I think it will help students learn how to read original research publications. –Professor Georgia Floyd Smith, Arizona State University

The coverage of ethics, particularly the box regarding the human genome project, is excellent. These are the types of side-trips that make teaching fun. A text which relates "issues" to the material makes the material relevant for students while giving the instructor an opportunity to lead an interesting discussion. –Professor Ellen Kittler, UMass Medical School


  • Each chapter includes end of chapter exercises, and references.

  • In-text examples and internet references are cited.

  • Most figures will be 2 color, with some 4 color inserts.