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Multi-Step Enzyme Catalysis: Biotransformations and Chemoenzymatic Synthesis

Multi-Step Enzyme Catalysis: Biotransformations and Chemoenzymatic Synthesis

Eduardo Garcia-Junceda (Editor)

ISBN: 978-3-527-62339-6

Nov 2008

256 pages



The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Multi-Enzyme Synthesis of Glycoconjugates
Multimodular Synthases as Tools of the Synthetic Chemist
Modifying the Glycosilation Pattern in Microorganisms by Combinatorial Biosynthesis
Chemoenzymatic Routes to Enantiomerically Pure Amines and Aminoacids
Asymmetric Transformations by Couples Enzymes and Metal Catalysis
Engineering Novel Biosynthetic Pathways to Produce New Chemical Compounds
Biocatalysis and Chemical Catalysis for the Synthesis of Intermediates of Pharmaceutical Interest
Oxidizing Enzymes into Multi-Enzyme Biotransformation Processes
The Role of Host-Intrinsic Enzyme Activities in Recombinant Whole-Cells Catalyzed Processes
Microbial Production of DNA Building Blocks
Enzyme Initiation of Asymmetric Cascade-Reactions
The System of Biotransformations Approach for Multi-Step Processes
Chemoenzymatic Synthesis of Homogeneous Glycoprotein
Aldolases Catalyzed C-C Bond Formation in the Core of Multi-Step Processes