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Multicomponent Reaction Chemistry: A Practical Approach

Multicomponent Reaction Chemistry: A Practical Approach

Alexander Dömling

ISBN: 978-3-527-80479-5

Jan 2022

500 pages


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Written by one of the world's leading experts in the field, this is the only book available to adopt a practical approach, presenting the most common and successful experimental procedures used in MCR.
As such, the book guides readers through the overwhelming amount of literature and points to the best procedures for gaining optimum results for the attempted synthesis. A small theoretical overview is presented and practical procedures described for each reaction covered. The examples are chosen from drug and natural product synthesis, parallel synthesis as well as drug discovery methods based on virtual screening of MCR-based libraries.
With its workable procedures this practical text is perfect for bench chemists working in the pharmaceutical and industrial chemistry, and can equally be used in an advanced organic chemistry or specialized course at universities.
Introduction to MCR
Isocyanide based MCR
Non isocyanide based MCR
Virtual Screening of MCR libraries
Chip based MCR
Polymers with MCR