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Myocardial Protection

Myocardial Protection

Tomas A. Salerno (Editor), Marco Ricci (Editor)

ISBN: 978-0-470-98745-2 October 2007 Wiley-Blackwell 344 Pages

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Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field.

The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

List of Contributors.


W. Gerard Rainer, MD.


Chapter 1. The History of Myocardial Protection.

Anthony L. Panos, MD, MSc, FRCSC, FACS.

Chapter 2. The Duality of Cardiac Surgery: Mechanical and Metabolic Objective.

Gerald D. Buckberg, MD.

Chapter 3. Modification of Ischemia-Reperfusion Induced Injury by Cardioprotective Interventions.

Ming Zhang, Tamer Sallam, Yan-Jun Xu, and Naranjan S. Dhalla.

Chapter 4. Anesthetic Preconditioning: A New Horizon in Myocardial Protection.

Nader D. Nader, MD, PhD, FCCP.

Chapter 5. Myocardial Protection During Acute Myocardial Infarct and Angioplasty.

Alexandre C. Ferreira, MD, FACC and Eduardo deMarchena, MD.

Chapter 6. Intermittent Aortic Cross Clamping for Myocardial Protection.

Fabio Biscegli Jatene, MD, PhD, Paulo Pêgo-Fernandes, MD, PhD, and Alexandre Ciappina Hueb, MD.

Chapter 7. Intermittent Warm Blood Cardioplegia: The Biochemical Background.

Ganghong Tian, MD, PhD, Tomas A. Salerno, MD, and Roxanne Deslauriers, PhD.

Chapter 8. Warm Heart Surgery.

Hassan Tehrani, MB, BCh, Atiq Rehman, MD, Pierluca Lombardi, MD, Mohan Thanikachalam, MD, and Tomas Salerno, MD.

Chapter 9. Intermittent Antegrade Warm Blood Cardioplegia.

Antonio Maria Calafiore, MD, Giuseppe Vitolla, MD, and Angela Iacò, MD.

Chapter 10. Antegrade, Retrograde, or Both?.

Frank G. Scholl, MD and Davis C. Drinkwater, MD.

Chapter 11. Miniplegia: Biological Basis, Surgical Techniques, and Clinical Results.

Giuseppe D’Ancona, MD, Hratch Karamanoukian, MD, Luigi Martinelli, MD, Michael O. Sigler, MD, and Tomas A. Salerno, MD.

Chapter 12. Substrate Enhancement in Cardioplegia.

Shafie Fazel, MD, Marc P. Pelletier, MD, and Bernard S. Goldman, MD.

Chapter 13. Is There a Place for On-Pump, Beating Heart Coronary Artery Bypass Grafting Surgery? The Pros and Cons.

Simon Fortier, MD, Roland G. Demaria, MD, and Louis P. Perrault, MD, PhD, FRCSC, FACS.

Chapter 14. Myocardial Protection in Beating Heart Coronary Artery Surgery.

Vinod H. Thourani, MD and John D. Puskas, MD, MSc.

Chapter 15. Beating Heart Coronary Artery Bypass Grafting: Intraoperative Strategies to Avoid Myocardial Ischemia.

Kushagra Katariya, MD, Michael O. Sigler, MD and Tomas A. Salerno, MD.

Chapter 16. Beating Heart Coronary Artery Bypass in Patients with Acute Myocardial Infarction: A New Strategy to Protect the Myocardium.

Jan F. Gummert, MD, PhD, Michael A. Borger, MD, PhD, Ardawan Rastan, MD, and Friedrich W. Mohr, MD, PhD.

Chapter 17. Beating Heart Coronary Artery Bypass with Continuous Perfusion Through the Coronary Sinus.

Harinder Singh Bedi, MCh, FIACS.

Chapter 18. On-Pump Beating Heart Surgery for Dilated Cardiomyopathy and Myocardial Protection.

Tadashi Isomura, MD and Hisayoshi Suma, MD.

Chapter 19. Myocardial Protection with b-Blockers in Valvular Surgery.

Nawwar Al Attar, FRCS, MSc, FETCS, Marcio Scorsin, MD, PhD, and Arrigo Lessana, MD, FETCS.

Chapter 20. Myocardial Protection in Minimally Invasive Valvular Surgery.

René Prêtre, MD and Marko I. Turina, MD.

Chapter 21. Intermittent Warm Blood Cardioplegia in Aortic Valve Surgery: An Update.

M. Saadah Suleiman, PhD, Raimondo Ascione, MD, and Gianni D. Angelini, MD, FRCS.

Chapter 22. Myocardial Protection in Surgery of the Aortic Root.

Stephen Westaby, PhD, MS, FETCS.

Chapter 23. Myocardial Protection in Major Aortic Surgery.

M.A. Schepens, MD, PhD and A. Nocchi, MD.

Chapter 24. Recent Advances in Myocardial Protection for Coronary Reoperations.

Jan T. Christenson, MD, PhD, FETCS and Afksendiyos Kalangos, MD, PhD, FETCS.

Chapter 25. Myocardial Protection During Minimally Invasive Cardiac Surgery.

Saqib Masroor, MD, MHS and Kushagra Katariya, MD.

Chapter 26. Current Concepts in Pediatric Myocardial Protection.

Bradley S. Allen, MD.

Chapter 27. Myocardial Preconditioning in the Experimental Model: A New Strategy to Improve Myocardial Protection.

Eliot R. Rosenkranz, MD, Jun Feng, MD, PhD, and Hong-Ling Li, MD, MSc.

Chapter 28. New Concepts in Myocardial Protection in Pediatric Cardiac Surgery.

Bindu Bittira, MD, MSc, Dominique Shum-Tim, MD, MSc, and Christo I. Tchervenkov, MD.

Chapter 29. Extracardiac Fontan: The Importance of Avoiding Cardioplegic Arrest.

Carlo F. Marcelletti and Raúl F. Abella.

Chapter 30. Myocardial Protection in Heart Failure and Transplantation Preservative Cardioplegic Solutions in Cardiac Transplantation: Recent Advances.

Romualdo J. Segurola Jr., MD and Rosemary F. Kelly, MD.

Chapter 31. Myocardial Preservation in Clinical Cardiac Transplantation: An Update.

Louis B. Louis IV, MD, Xiao-Shi Qi, MD, PhD, and Si M. Pham, MD, FACS.

Chapter 32. Myocardial Protection During LVAD Implantation.

Aftab R. Kherani, MD, Mehmet C. Oz, MD, and Yoshifumi Naka, MD, PhD.

Chapter 33. Gene Therapy for Myocardial Protection.

Said F. Yassin, MD and Christopher G. McGregor, MD .


  • An up to date presentation of myocardial protective strategies being utilised by surgeons performing different procedures

  • The text has been intentionally orientated to the present and the future

  • International contributor list