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Neuroprotection: Models, Mechanisms and Therapies

Neuroprotection: Models, Mechanisms and Therapies

Mathias Bähr (Editor)

ISBN: 978-3-527-60431-9

Mar 2006, Wiley-Blackwell

390 pages

$193.99

Description

In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders.
Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
INTRODUCTION AND OVERVIEW
Problems and Possibilities of Bridging Between Basic Research and Clincal Applications
EPIDEMIOLOGY AND CLINICAL OVERVIEW OF NEUROLOGICAL DISORDERS AND RESPECTIVE MODEL SYSTEMS
Stroke
Parkinson's Disease
Amyotrophic Lateral Sclerosis
Alzheimer's Disease
Epilepsy
CNS Inflammation
Brain Trauma
Spinal Cord Trauma
CELLULAR AND MOLECULAR MECHANISMS
Apoptosis/Necrosis
Inflammation
Metabolic Dysfunctions
Protein Aggregation
Axonal Growth and Growth Inhibition
Neurogenesis
CLINICAL STUDIES
Stroke
Trauma
Neurodegeneration
PERSPECTIVES
Current Challenges
Development of Effective Treatment Strategies in the Future
"... a very good resource for a broad range of readers"
E-STREAMS, March 2005

"The text is well-written, corresponds to the needed concepts and reflects the current understanding of the topic."
Doody's Health Services


"...Bähr has succeeded in bringing together experts from...[basic researchers and experienced clinicians] to contribute to this book - a collaboration that is also needed for advancement in the field."
New England Journal of Medicine, May 26, 2005

"The book is clearly written, well referenced and equally important for basic neuroscientists, clinicians and young researchers. (...) This book is a wonderful compilation of high standard reviews. (...) Overall, this is a nicely concised book and we recommend it as one of the reference books for both basic neuroscientists and clinicians."
Journal of Chemical Neuroanatomy