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Neuroprotection: Models, Mechanisms and Therapies

Neuroprotection: Models, Mechanisms and Therapies

Mathias Bähr (Editor)

ISBN: 978-3-527-60431-9

Mar 2006, Wiley-Blackwell

390 pages

Select type: E-Book

$193.99

Description

In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders.
Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
INTRODUCTION AND OVERVIEW
Problems and Possibilities of Bridging Between Basic Research and Clincal Applications
EPIDEMIOLOGY AND CLINICAL OVERVIEW OF NEUROLOGICAL DISORDERS AND RESPECTIVE MODEL SYSTEMS
Stroke
Parkinson's Disease
Amyotrophic Lateral Sclerosis
Alzheimer's Disease
Epilepsy
CNS Inflammation
Brain Trauma
Spinal Cord Trauma
CELLULAR AND MOLECULAR MECHANISMS
Apoptosis/Necrosis
Inflammation
Metabolic Dysfunctions
Protein Aggregation
Axonal Growth and Growth Inhibition
Neurogenesis
CLINICAL STUDIES
Stroke
Trauma
Neurodegeneration
PERSPECTIVES
Current Challenges
Development of Effective Treatment Strategies in the Future

"In diesem sehr ansprechend zusammengestellten Buchband geben international ausgewiesene Neurodegenerationsforscher einen Einblick in das Gebiet zentralnervöser Neurodegeneration und Neuroprotektion."

D. Hermann, Zürich, Schweizer Archiv für Neurologie und Psychiatrie, 2/2005