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Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects, 2nd, Completely Revised and Enlarged Edition

Neurotransmitters and Neuromodulators: Handbook of Receptors and Biological Effects, 2nd, Completely Revised and Enlarged Edition

Oliver von Bohlen und Halbach, Rolf Dermietzel

ISBN: 978-3-527-60996-3

Dec 2006, Wiley-Blackwell

402 pages

Description

A complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators. The coverage is now even more comprehensive, with 15% more entries on neuropeptides, "classic" neurotransmitters and related substances in a clear, alphabetical format. The methodological section has been expanded by 50% and now includes color figures, plus new chapters on genomics, proteomics, databases, microarrays, MALDI-TOF, neutrophins, FGF, endocannabinoids and neuroimaging. The text provides clearly structured information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system, with all substances uniformly treated for an easy comparison of data. Furthermore, introductory chapters on receptors, transporters, and the blood-brain barrier make this an indispensable tool for researchers, teachers, and advanced students, as well as a must-have for every neuroscientist.
INTRODUCTION
Neuroactive Substances
Receptors and Transporters
Distribution and Localization of Neurotransmitters and Neuromodulators
The Blood-Brain Barrier
Volume Transmission and Wiring Transmission
METHODS FOR STUDYING NEUROACTIVE SUBSTANCES
Bio- and Radioisotope Assays
Microdialysis and Electrochemical Detection
Chromatography
Autoradiography
Immunohistochemical Methods
In-situ Hybridization
Staining and Neuroanatomical Tract Tracing
Electrophysiology
Behavioral Testing
Microarrays
MALDI-TOF
Neuroimaging
Genomics und Proteomics Methods
Databases
NEUROTRANSMITTERS
Acetylcholine
Dopamine
GABA (Gamma-Amino Butyric Acid)
Glutamate and Aspartate
Glycine
Histamine
Norepinephrine
Serotonin (5-hydroxytryptamine)
NEUROMODULATORS
Adrenocorticotropic Hormone (ACTH)
Anandamide
Angiotensin
Atrial Natriuretic Factor
Calcitonin and Calcitonin Gene-Related Protein
Cholecystokinin
Corticotropin-Releasing Factor (CRF)
Dynorphin
Eicosanoids and Arachidonic Acid
Endocannabinoids
Endorphin
Enkephalin
FGF
Galanin
Growth Hormone-Releasing Hormone
Gonadotropin-Releasing Hormone
Interleukin
Melanin-Concentrating Hormone
Melanocyte-Stimulating Hormone
Neurotensin
Neutrophins
Nitric Oxide
Nociceptin (Orphanin FQ)
Neuropeptide Y
PACAP (pituitary adenylate cyclase-activating polypeptide)
Proopiomelanocortin
Purines
Somatostatin
Substance P and Tachykinins
Thyrotropin-Releasing Hormone
Tyr-MIF-1 Family
Vasoactive Intestinal Polypeptide (VIP)
Vasopressin and Oxytocin