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Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

Yoshinori Mine (Editor), Kazuo Miyashita (Editor), Fereidoon Shahidi (Editor)

ISBN: 978-0-813-80726-3 June 2009 Wiley-Blackwell 412 Pages

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Description

Part of the Functional Food Science and Technology book series (Series Editor: Fereidoon Shahidi), this book compiles the current science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals (food factors) and their impact on gene interaction and health. Authored by a stellar international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date.

Preface vii

Contributors ix

Section I Introduction

1. Nutrigenomics and Proteomics in Health and Disease: An Overview 3
Yoshinori Mine, Kazuo Miyashita, and Fereidoon Shahidi

2. Omics in Nutrition and Health Research 11
Michael Affolter, Frédéric Raymond, and Martin Kussmann

Section II Genomics and Proteomics in Health and Diseases

3. Toward Personalized Nutrition and Medicine: Promises and Challenges 33
Baitang Ning and Jim Kaput

4. Obesity and Nuclear Receptors: Effective Genomic Strategies in Functional Foods 47
Teruo Kawada, Tsuyoshi Goto, Shizuka Hirai, Rina Yu, and Nobuyuki Takahashi

5. Inflammatory Genes Involved in Obesity-Induced Inflammatory Responses and Pathologies 59
Rina Yu

6. Genomics and Proteomics in Allergy 67
Icy D’Silva and Yoshinori Mine

Section III Food Factors–Gene Interactions

7. Beneficial Effects of Conjugated Linoleic Acid 85
Kazunori Koba and Teruyoshi Yanagita

8. Regulation of Gene Transcription by Fatty Acids 97
Jean-Paul Pégorier

9. Nonnutrient Functionality of Amino Acids 115
Yoshinori Mine and Connie J. Kim

10. Functional Bioactive Proteins and Peptides in Nutrigenomics 129
Denise Young and Yoshinori Mine

11. Antiobesity Effect of Allenic Carotenoid, Fucoxanthin 145
Kazuo Miyashita and Masashi Hosokawa

12. Control of Systemic Inflammation and Chronic Diseases—The Use of Turmeric and Curcuminoids 161
Stig Bengmark

13. Alteration in Gene Expression and Proteomic Profiles by Soy Isoflavone 181
Fazlul H. Sarkar and Yiwei Li

14. Green Tea Polyphenol-Modulated Genome Functions for Protective Health Benefits 201
Molay K. Roy, Mahendra P. Kapoor, and Lekh R. Juneja

15. Oat Avenanthramides: A Novel Antioxidant 239
Li Li Ji, Ryan Koenig, and Mitchell L. Wise

16. Cancer-Preventive Effects and Molecular Actions of Anthocyanins 251
De-Xing Hou

17. Food Components Activating Capsaicin Receptor TRPV1 263
Tatsuo Watanabe, Yusaku Iwasaki, Akihito Morita, and Kenji Kobata

18. New Therapeutic Effects of Anthocyanins: Antiobesity Effect, Antidiabetes Effect, and Vision Improvement 273
Takanori Tsuda and Hitoshi Matsumoto

19. Licorice Flavonoids 291
Shinichi Honda, Yuji Tominaga, and Shinichi Yokota

20. Isoprenols 301
Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai, and Teruo Kawada

21. Anti-inflammatory and Anticarcinogenesis Potentials of Citrus Coumarins and Polymethylated Flavonoids 311
Akira Murakami and Hajime Ohigashi

22. Probiotics: Food for Thought 325
Kingsley C. Anukam and Gregor Reid

Section IV Advanced Analytical Techniques for Nutrigenomics and Proteomics

23. Microarrays: A Powerful Tool for Studying the Functions of Food and Its Nutrients 341
Hiroshi Mano, Jun Shimizu, and Masahiro Wada

24. Challenges and Current Solutions in Proteomic Sample Preparations 351
Feng Tao

25. Computational Methods in Cancer Gene Networking 367
Edwin Wang

26. Peptidomics 375
Yoshinori Mine

Index 387 

"Nutrigenomics and Proteomics in Health and Disease contains a wealth of information, though because of the variety of contributors its focus is somewhat scattered - it does not even aim to provide a ‘conclusive' view (if such was even possible), but rather a variety of perspectives and different kinds of research." (Suite101.com, 7 October 2010)

  • Key resource for current researchers and practitioners in nutrigenomics
  • Describes links between foods, diseases and health
  • Extensive, rigorous coverage of food factors-gene interactions
  • Respected international collection of editors and authors