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Nutritional Genomics: Impact on Health and Disease



Nutritional Genomics: Impact on Health and Disease

Regina Brigelius-Flohé (Editor), Hans-Georg Joost (Editor)

ISBN: 978-3-527-31294-8 March 2006 Wiley-Blackwell 470 Pages


Nutritional genomics paves the way for novel applications in medicine and human nutrition, and this volume presents the latest data on how genetic variation is associated with dietary response and how nutrients influence gene expression. In so doing, it brings together the various disciplines involved in this field of research, making this essential reading for nutritionists, biochemists and molecular biologists.
Nutritional Genomics: Concepts, Tools and Expectations
Nuclear Receptors: An Overview
Mechanism of Action and Cancer Therapeutic Potential of Retinoids
Nuclear Receptors and the Control of Gene Expression by Fatty Acids
Cellular Adaptation to Amino Acid Availability: Mechanisms Involved in the Regulation of Gene Expression
Transcriptional Regulation of Hepatic Genes by Insulin and Glucose
PPARs: Lipid Sensors that Regulate Cell Differentiation Processes
Advances in Selenoprotein Expression: Patterns and Individual Variations
PPARs in Atherosclerosis
Protein Synthesis and Cancer
Mutations in the PPAR Gene Relevant for Diabetes and the Metabolic Syndrome
Regulation of Lipogenic Genes in Obesity
The Genetics of Type 2 Diabetes
Gene Variants and Obesity
Gene Polymorphisms, Nutrition, and the Inflammatory Response
Gene Variants, Nutritional Parameters, and Hypertension
Gene Variants, Nutrition, and Cancer
Taste Receptors and their Variants
Cancer and Gene Variants in Enzymes Metabolizing Dietary Xenobiotics