Skip to main content


Organic Chemistry, 3rd Edition

David R. Klein

ISBN: 978-1-119-44425-1 August 2017 1312 Pages


In Organic Chemistry, 3rd Edition, Dr. David Klein builds on the phenomenal success of the first two editions, which presented his unique skills-based approach to learning organic chemistry. Dr. Klein’s skills-based approach includes all of the concepts typically covered in an organic chemistry textbook, and places special emphasis on skills development to support these concepts. This emphasis on skills development in unique SkillBuilder examples provides extensive opportunities for two-semester Organic Chemistry students to develop proficiency in the key skills necessary to succeed in organic chemistry.

Related Resources


View Instructor Companion Site

Contact your Rep for all inquiries

1. A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

2. Molecular Representations

3. Acids and Bases

4. Alkanes and Cycloalkanes

5. Stereoisomerism

6. Chemical Reactivity and Mechanisms

7. Substitution and Elimination Reactions of Alkyl Halides

8. Addition Reactions of Alkenes

9. Alkynes

10. Radical Reactions

11. Synthesis

12. Alcohols and Phenols

13. Ethers and Epoxides; Thiols and Sulfides

14. Infrared Spectroscopy and Mass Spectrometry

15. Nuclear Magnetic Resonance Spectroscopy

16. Conjugated Pi Systems and Pericyclic


17. Aromatic Compounds

18. Aromatic Substitution Reactions

19. Aldehydes and Ketones

20. Carboxylic Acids and Their Derivatives

21. Alpha Carbon Chemistry: Enols and Enolates

22. Amines

23. Organometallic Reactions

24. Carbohydrates

25. Amino Acids, Peptides, and Proteins

26. Lipids

27. Synthetic Polymers

  • Author-curated WileyPLUS course- offering instructors a pre-built suite of assignments tailored to the way David Klein teaches his course
  • ACS-style problem sets in each chapter: providing students practice on solving problems similar to what they will encounter on the ACS exam
  • Interactive graphics embedded in every chapter: provides students with drag and drop- style assessment on mechanism problems (over 300 total)
  • E-book-embedded, auto-graded practice problems in every chapter, (over 500 total)
  • 3D Molecular Visualizations, Reaction Explorer Mechanisms embedded in each chapter
  • Mid-level literature based problems- offering students sample problems based “real world” applications (or cases) that have been published in professional journals
  • Author-created Solved Problem Videos, over (200 total)
  • ORION, adaptive practice questions for Polymers and Transition Metal chapters
  • Chapter on organometallic reactions covers modern synthetic techniques, including Stille coupling, Suzuki coupling, Negishi coupling, the Heck reaction, and alkene metathesis.
  • Substitution and elimination reactions have been combined into one chapter (chapter 7) to better show the relationship between these two important concepts
  • Fully integrated ebook with embedded multi-media content 
  • WileyPLUS is a research-based online environment for effective teaching and learning. WileyPLUS is packed with interactive study tools and resources–including the complete online textbook–giving your students more value for their money. With WileyPLUS, students are provided with unique study strategies, tools, and support based on learning styles for success in Organic Chemistry. WileyPLUS hallmarks, such as Reaction Explorer, remain alongside brand-new course updates.
  • SkillBuilder Approach illustrated by the SKILLBUILDER Examples. David Klein's skills-based approach helps students succeed by providing step-by-step, problem-solving guidance that facilitates conceptual understanding of the core concepts in Organic Chemistry. Special emphasis is placed on drawing resonance structures, predicting products, proposing mechanisms, proposing syntheses, and drawing mechanisms. SkillBuilders are broken into 3 parts:
      • Learn the Skill
      • Practice the Skill
      • Apply the Skill
  • Conceptual Checkpoints exercises appear after many sections to give students practice of the recently presented concepts.
  • Approximately 100 Medically Speaking & Practically Speaking application boxes demonstrate relevancy of organic chemistry to medicine, current research, and the world around us.
  • Chapter Openers contain a “Did You Ever Wonder” question that serve to capture the students’ interest. These questions are answered within that chapter.