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Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocycles

Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocycles

Min Shi, Yin Wei, Mei-Xin Zhao, Dr. Jun Zhang

ISBN: 978-3-527-80730-7

Jun 2018

350 pages

$152.99

Product not available for purchase

Description

A comprehensive resource to the development and recent progress of zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes

Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocycles offers a clear explanationto thedevelopment of and the information on the latest research pertaining to zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes. The authors—noted experts in the field—include a comprehensive review to the investigations of the reaction mechanisms and explore the synthesis of different products from the same starting materials. 

Filled with illustrative examples and designed to be accessible, the text shows how to control the chemo-, regio- and stereoselectivity and explains the further design of novel cycloaddition reactions catalyzed by organoamines and organophosphines based on zwitterion-oriented synthetic strategy. This important text:

  • Explains why the formation of carbo- and heterocycles is a key transformation in organic synthesis.
  • Offers a clear description to the development of zwitterion-oriented cycloadditions promoted by organoamines, organophosphines, N-heterocyclic carbenes, and explores the latest research
  • Contains the most current examples involving synthetic transformations of organocatalytic cycloadducts
  • Includes contributions from noted experts in the field of organic synthesis

Written for organic chemists, pharmaceutical chemists, chemists in industry, graduates, and librarians, Organocatalytic Cycloadditions for Synthesis of Carbo- and Heterocyclesis is the essential guide to the topic.

Chapter 1 Introduction to Organocatalytic Cycloaddition
1.1 Brief introduction to organocatalytic cycloadditions for synthesis of carbo- and heterocycles
1.2 General mechanistic insights into cycloadditions promoted by nucleophilic organocatalysts

Chapter 2 Cycloadditions Catalyzed by Organoamines
2.1 Introduction
2.2 [2+2] cycloadditions
2.3 [3+2] cycloadditions
2.4 [4+2] cycloadditions
2.5 Domino reactions
2.6 Miscellaneous reactions

Chapter 3 Cycloadditions Catalyzed by Organophosphines
3.1 Introduction
3.2 [2+2] cycloadditions
3.3 [3+2] cycloadditions
3.4 [4+n] cycloadditions
3.5 Domino reactions
3.6 Miscellaneous reactions

Chapter 4 Cycloadditions Catalyzed by N-heterocyclic Carbenes
4.1 Introduction
4.2 [2+2] cycloadditions
4.3 [3+2] cycloadditions
4.4 [4+2] cycloadditions
4.5 Domino reactions
4.6 Miscellaneous reactions

Chapter 5 Synthetic Transformations of Organocatalytic Cycloadducts
The latest interesting examples involve synthetic transformations of organocatalytic cycloadducts

Appendix
The latest interesting reports and overlook may be included in this part. Some interesting reports may appear during the book review process.