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Pharmacology: From Drug Development to Gene Therapy

Robert A. Meyers (Editor)

ISBN: 978-3-527-32343-2 June 2008 Wiley-Blackwell 1126 Pages


This invaluable collection of high-quality articles on pharmacology is taken from the tried-and-tested Meyers' Encyclopedia of Molecular Cell Biology and Molecular Medicine whose editorial board includes 12 Nobel laureates.
Divided into four main sections, this attractive handbook covers essential fields in pharmacology, from drug development to cancer and gene therapy.
The articles are uniformly structured for ease of use and carefully designed to serve readers of all levels of expertise. Each chapter includes a glossary of the most important keywords, a concise summary of the article and a comprehensive literature references.
The book is a must have reference work for pharmacology departments in academia as well as for the pharmaceutical industry.

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Medicinal Chemistry
Biotransformations of Drugs and Chemicals
Disposition and Clearance Prediction of Drug Bioavailability
Pharmacokinetics and Pharmacodynamics of Biotech Drugs
Targeting and Intracellular Delivery of Drugs
Pharmacogenomics and Drug Design
Chemistry, Biology, and Drug Design of Synthetic Peptides:
Structure-based Drug Design and NMR-based Screening
Receptor Targets in Drug Discovery
Therapeutic Compounds in Nature as Leads for New Pharmaceuticals
Cancer Stem Cells
Plant-based Expression of Biopharmaceuticals
Genetic Engineering of Antibody Molecules
Exploiting Model Organisms for Disease Intervention
Pharmacology and Emerging Clinical Application of RNA
Biochemistry of HIV Therapeutics
Xenotransplantation in Pharmaceutical Biotechnology
RNA Interference
Genomic Approaches in Targeted Therapy
Therapeutic Angiogenesis
Molecular Oncology
Theoretical Foundations of Cancer Chemotherapy
Antitumor Steroids
Immunotoxins and Recombinant Immunotoxins in Cancer Therapy
Liposome Gene Transfection
Genetic Vaccination
Vectors and Gene Therapy
Somatic Gene Therapy
Virus-free Gene Transfer Systems in Somatic Gene Therapy
Gene Therapy and Cardiovascular Diseases
Vector System: Plasmid DNA
Vector Targeting in Gene Therapy
An outstanding, authoritative, single-source reference on molecular aspects of pharmacology from drug development to gene therapy. (Doody's, July 2008)