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Plasticity of the Neuromuscular System



Plasticity of the Neuromuscular System

David Evered (Editor), Julie Whelan (Editor)

ISBN: 978-0-470-51368-2 April 2008 284 Pages


Presents new information on the mutual interaction of skeletal muscle fibers and motoneurons at all levels, from the physiological to the molecular. Covers genetic, physiological, and hormonal factors affecting skeletal muscle development, control of acetylcholine receptor gene expression, selection and organization of motoneurons, and remodelling and refinement of synaptic inputs under the influence of muscle-derived growth factors. Also discusses the plasticity of the neuromuscular system during regeneration after injury, and in the modification of muscle properties and movement patterns in disease states by changes in sensory input or by electrical stimulation.
Partial table of contents:

Physiological Factors Influencing the Growth of Skeletal Muscle (R. Eisenberg, et al.).

Hormonal Control of Myosin Heavy Chain Genes During Development of Skeletal Muscles (N. Rubinstein, et al.).

Mechanisms of Interaction Between Motoneurons and Muscles (M. Brown & E. Lunn).

In Vitro Analysis of Specificity during Nerve--Muscle Synaptogenesis (D. Sanes & M. Poo).

Reorganization of Synaptic Inputs to Developing Skeletal Muscle Fibers (G. Vrbová, et al.).

The Role of Muscle in the Development and Differentiation of Spinal Mq6 Neurons: In Vitro Studies (C. Henderson).

Comparison of Injury and Development in the Neuromuscular System (T. Gordon, et al.).

Responses of Diseased Muscle to Electrical and Mechanical Intervention (V. Dubowitz).

Subject Index.