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Radicals in Organic Synthesis

Radicals in Organic Synthesis

Philippe Renaud (Editor), Mukund P. Sibi (Editor)

ISBN: 978-3-527-61829-3 March 2008 1158 Pages


Over the past few years, radical chemistry has witnessed a rapid development, with the result, for example, that new methods for producing radicals now allow the targeted use of these reactive intermediate stages in organic synthesis. This two-volume work is an account of the progress being made.
The first volume covers basic methodologies for successfully carrying out radical reactions, complete with a detailed discussion of the effectiveness and versatility of the individual methods. Further, the first volume also treats the characteristics of radicals, where such information is necessary for the successful planning of synthesis.
The second volume concentrates on applications for radicals in synthesis. Of particular use to those working in research are the numerous comparisons to "classic" methods of synthesis, carefully collected from the editors' and authors' many years of experience in the field.
The vast amount of information contained in this work makes it an essential reference for every organic chemist working in industry and academia.
Radical chain reactions
Single electron
Properties of radicals
Stereoselectivity of radical reactions
Cascade reactions
Radical rearrangements
Miscellaneous applications
Radicals in total synthesis
Heteroatom centered radicals
Radicals in biomaterials
"Many of the 76 contributors are leading workers in the field, and the result is two beautifully produced volumes which should most certainly find their way into every laboratory where organic synthesis is practised." (The Alchemist,, 22 November, 2001)

"...a valuable resource for synthetic chemists for years to come.... I recommend these books to anyone who has a serious interest..." (Journal of the American Chemical Society, Vol. 124, No. 40, 2002)