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Reproductive Biomechanics, Volume 1101



Reproductive Biomechanics, Volume 1101

David Elad (Editor), Roger C. Young (Editor)

ISBN: 978-1-573-31673-6 May 2007 Wiley-Blackwell 352 Pages


The reproductive system is composed of complex sub-systems, which are driven by sophisticated biochemical processes, whereas their performance is controlled by the same physical laws that exist in any mechanical process on Earth (e.g., Newton's laws).

Accordingly, the understanding of any physiological phenomenon, including the development of a pathologic condition, requires comprehensive evaluation of the biophysical and biomechanical aspects of reproduction in concert with the biological and clinical features. Several of the scientists from around the world who investigate the physical aspects of the reproductive system have contributed to the eight sessions resulting in this volume.

These reports encompass the following areas of inquiry: non-pregnant uterine peristalsis, placental vasculature and blood flow, myometrial contractility and calcium transport, mechanics of the uterus and cervix in pregnancy, mechanics of embryonic development, penile mechanics and hemodynamics, sperm propulsion, and pelvic floor mechanics.

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Part I: Nonpregnant Uterine Peristalsis:.

1. Physiology of Upward Transport in the Human Female Genital Tract: I. Zervomanolakis, H.W. Ott, D. Hadziomerovic, V. Mattle, B. E. Seeber, I. Virgolini, D. Heute, S. Kissler, G. Leyendecker, and L. Wildt.

2. Bioengineering Studies of the Embryo Transfer Procedure: Osnat Eytan, David Elad, and Ariel J. Jaffa.

3. Utero-Tubal Sperm Transport and Its Impairment in Endometriosis and Adenomyosis: Stefan Kissler, Stephan Zangos, Inka Wiegratz, Joachim Kohl, Achim Rody, Regine Gaetje, Natascha Doebert, Ludwig Wildt, Georg Kunz, Gerhard Leyendecker, and Manfred Kaufmann.

4. Uterine Contractility: Visualization of Synchronization Measures in Two Simultaneously Recorded Signals: Edward Oczeretko, Agnieszka Kitlas, Marta Borowska, Jolanta Swiatecka, and Tadeusz Laudanski.

5. Uterine Contractility Evaluated on Cine Magnetic Resonance Imaging: Kaori Togashi.

Part II: Myometrial Contractility and Calcium Transport:.

6. Myocytes, Myometrium, and Uterine Contractions: Roger C. Young.

7. In Situ Calcium Signaling: No Calcium Sparks Detected in Rat Myometrium: Theodor Burdyga, Susan Wray, and Karen Noble.

8. Control of Uterine Ca2+ by Membrane Voltage: Toward Understanding the Excitation–Contraction Coupling in Human Myometrium: Anatoly Shmygol, Andrew M. Blanks, Gilles Bru-Mercier, Joanna E. Gullam, and Steven Thornton.

9. Modeling Myometrial Smooth Muscle Contraction: Limor Bursztyn, Osnat Eytan, Ariel J. Jaffa, and David Elad.

10. Interstitial Cajal-Like Cells in Human Uterus and Fallopian Tube: Laurentiu M. Popescu, Sanda M. Ciontea, Anddragos Cretoiu.

Part III: Mechanics of the Uterus and Cervix in Pregnancy:.

11. Microstructure and Mechanics of the Chorioamnion Membrane with an Emphasis on Fracture Properties: Steven E. Calvin and Michelle L. Oyen.

12. In Vivo Characterization of the Mechanics of Human Uterine Cervices: Margit Bauer, Edoardo Mazza, Alessandro Nava, Willibald Zeck, Martina Eder, Michael Bajka, Fernando Cacho, Uwe Lang, and Gerhard A. Holzapfel.

13. Analysis of Cervical Dynamics by Ultrasound Imaging: Rimma Pugatsch, David Elad, Ariel J. Jaffa, and Osnat Eytan.

Part IV: Placental Vasculature and Blood Flow:.

14. Twin–Twin Transfusion Syndrome Modeling: Jeroen P. H. M. Van Den Wijngaard, Michael G. Ross, and Martin J. C. Van Gemert.

15. Modeling Acardiac Twin Pregnancies: Rosa De Groot, Jeroen P. H. M. Van Den Wijngaard, Asli Umur, Johan F. Beek, Peter G. J. Nikkels, and Martin J. C. Van Gemert.

16. Fetal Blood Flow in Branching Models of the Chorionic Arterial Vasculature: Zoya Gordon, Osnat Eytan, Ariel J. Jaffa, and David Elad.

Part V: Pelvic Floor Mechanics:.

17. Functional Anatomy of the Female Pelvic Floor: James A. Ashton-Miller and John O. L. Delancey.

18. Evaluation of the Dynamic Responses of Female Pelvic Floor Using a Novel Vaginal Probe: Chris E. Constantinou, Sadao Omata, Yasukuni Yoshimura, and Qiyu Peng.

19. Finite Element Studies of the Deformation of the Pelvic Floor: J. A. C. Martins, M. P. M. Pato, E. B. Pires, R. M. Natal Jorge, M. Parente, and T. Mascarenhas.

20. A Contextual Model of Pelvic Floor Muscle Defects in Female Stress Urinary Incontinence: A Rationale for Physiotherapy Treatment: Stephanie J. Madill and Linda Mclean.

21. Magnetic Resonance-Based Female Pelvic Anatomy as Relevant for Maternal Childbirth Injury Simulations: Lennox Hoyte and Margot S. Damaser.

Part VI: Mechanics of Embryonic Development:.

22. Cardiovascular Developmental Insights from Embryos: Bradley B. Keller, Li J. Liu, Joseph P. Tinney, and Kimimasa Tobita.

23. Mechanobiology of Embryonic Limb Development: Niamh C. Nowlan, Paula Murphy, and Patrick J. Prendergast.

24. Hedgehog Signaling: A Biophysical or Biomechanical Modulator in Embryonic Development?: Takashi Nagase, Miki Nagase, Masafumi Machida, and Masaaki Yamagishi.

Part VII: Penile Mechanics and Hemodynamics:.

25. A Mathematical Model of Penile Vascular Dysfunction and Its Application to a New Diagnostic Technique: Ofer Barnea, Shimon Hayun, and Gabriel Gillon.

26. Penises as Variable-Volume Hydrostatic Skeletons: Diane A. Kelly.

27. A Three-Dimensional Model of the Penis for Analysis of Tissue Stresses during Normal and Abnormal Erection: Eran Linder-Ganz, Amit Gefen, David Elad, and Juza Chen.

Part VIII: Sperm Propulsion:.

28. The Geometric Clutch as a Working Hypothesis for Future Research on Cilia and Flagella: Charles B. Lindemann.

29. Fluid Dynamic Models of Flagellar and Ciliary Beating: Robert H. Dillon, Lisa J. Fauci, Charlotte Omoto, and Xingzhou Yang.

30. Molecular Basis of Sperm Flagellar Axonemes: Structural and Evolutionary Aspects: Kazuo Inaba.

Index of Contributors