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Rossi's Principles of Transfusion Medicine, 4th Edition

Rossi's Principles of Transfusion Medicine, 4th Edition


Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available. It features brand new chapters on the measurement of cell kinetics, obstetric transfusion practice, cord blood, transfusion alternatives and regenerative medicine. Produced jointly with AABB, the world's leading association in the fields of blood banking and transfusion medicine, it now has two companion CD-ROMs-one containing interactive case studies and one containing PDFs of all 66 chapters.


1 Transfusion in the New Millennium: Ennio C. Rossi and Toby L. Simon.

Section I. Blood Components and Derivatives.

Part I. Red Blood Cells.

2 Red Cell Production and Kinetics: Mark J. Koury.

3 Regulation of Oxygen Delivery by Red Cells and Red Cell Substitutes: Christopher P. Stowell.

4 Red Blood Cell Metabolism and Preservation: Bjarte G. Solheim and John R. Hess.

5 Red Cell Immunology and Compatibility Testing: W. John Judd.

6 Carbohydrate Blood Groups: Eldad A. Hod, Patrice Spitalnik and Steven L. Spitalnik.

7 Rh and LW Blood Groups: Connie M. Westhoff and Don L. Siegel.

8 Other Protein Blood Groups: Petr Jarolim.

9 Anemia and Red Blood Cell Transfusion: Jeffrey L. Carson and Paul C. Hébert.

Part II. Platelets.

10 Platelet Production, Kinetics, and Hemostasis: Henry M. Rinder and Aaron Tomer.

11 Platelet Immunology and Alloimmunization: Brian R Curtis and Janice G. McFarland.

12 Preparation, Preservation, and Storage of Platelet Concentrates: Ralph R. Vassallo, Jr.

13 Thrombocytopenia and Platelet Transfusio: Peter W. Marks.

Part III. White Blood Cells.

14 Neutrophil Production and Kinetics: Neutropenia and Neutrophilia: Thomas H. Price.

15 Neutrophil Collection and Transfusion: Ronald G. Strauss.

16 Leukocyte-Reduced Blood Components: Laboratory and Clinical Aspects: Darrell J. Triulzi and Walter H. Dzik.

Part IV. Plasma.

17 Composition and Mechanisms of Blood Coagulation and Fibrinolysis: Peter Hellstern.

18 Immunoglobulins: Urs E. Nydegger.

19 Preparation and Use of Plasma Derivatives: Toby L. Simon, Kirsten Seidel and Albrecht Gröner.

20 Plasma Transfusion and Use of Albumin: Simon J. Stanworth and Alan T. Tinmouth.

Part V. Cell Kinetics.

21 Applications of Cellular Radiolabeliing in Transfusion Medicine: Larry J. Dumont, James P. AuBuchon and Richard J. Davey).

Section II. Clinical Practice.

Part I. Medical Patients.

22 Autoimmune Hemolytic Anemia and Paroxysmal Noctural Hemoglobinuria: Thomas P. Duffy.

23 Management of Immune Thrombocytopenias: Donald M. Arnold, James W. Smith and Theodore Warkentin.

24 Bleeding from Acquired Coagulation Defects and Antithrombotic Therapy: Thomas J. Raife, Jeffry S. Rose and Steven R. Lentz.

Part II. Obstetric and Pediatric Patients.

25 Fetal and Neonatal Hematopoiesis: Robert D. Christensen and Martha C. Sola-Visner.

26 Obstetric Transfusion Practice: Humphrey H.H. Kanhai, Jos J.M. van Roosmalen and Anneke Brand.

27 Hemolytic Disease of the Newborn: Bjarte G. Solheim and Morten Grönn.

28 Congenital Disorders of Clotting Proteins and Hypercoagulable States in Pediatrics: Linda J. Butros and Prasad Mathew.

29 Management of Congenital Hemolytic Anemias: Bruce I. Sharon.

30 Blood Component Transfusions for Infants: Ronald G. Strauss.

Part III. Oncology Patients.

31 Transfusion Support for the Oncology Patient: Christopher A. Tormey and Edward L. Snyder.

32 Hematopoietic Growth Factors (Cytokines): W. Conrad Liles and David C. Dale.

33 Hematopoietic Progenitor Cells: Biology and Processing: Thomas Leemhuis and Ronald A. Sacher.

34 Hematopoietic Progenitor Cells: Autologous Transplantation: Hooman H. Rashidi and Scott D. Rowley.

35 Hematopoietic Progenitor Cells: Allogeneic Transplantation: Amin M. Alousi and Sergio A. Giralt.

36Umbilical Cord Blood: A Reliable Source of Stem and Progenitor Cells for Human Transplantation: Suhag H. Parikh and Joanne Kurtzberg.

Part IV. Surgery Patients.

37 Alternatives to Transfusion: Perioperative Blood Management: Lynne Uhl.

38 Blood Components to Achieve Hemostasis for Surgery and Invasive Procedures: Walter H Dzik.

39 Transfusion Therapy in the Care of Trauma and Burn Patients: Ellen C. Omi and Richard L. Gamelli.

40 Transfusion Therapy in Solid-Organ Transplantation: Glenn Ramsey.

Section III. Apheresis.

41 Apheresis: Principles and Technology of Hemapheresis: Ronald O. Gilcher and James W. Smith.

42 Therapeutic Plasma Exchange Bruce C. McLeod.

43 Specialized Therapeutic Hemapheresis and Phlebotomy: Robert Weinstein.

Section IV. Hazards of Transfusion.

Part I - Hemovigilance.

44 Overview of Hemovigilance: Dorothy Stainsby, Jean-Claude Faber and Jan Jørgensen.

45 Immunomodulatory and Proinflammatory Effects of Allogeneic Blood Tranfusion: Eleftherios C. Vamvakas, José O. Bordin and Morris A. Blajchman.

Part II. Infectious Hazards of Transfusion.

46 Transfusion-Transmitted Hepatitis: Harvey J. Alter and Juan I. Esteban-Mur.

47 Retroviruses and Other Viruses: John A. J. Barbara and Brian Dow.

48 Transfusion Transmission of Parasites: Bryan R. Spencer.

49 Bacterial Contamination of Blood Products: Yara A. Park and Mark E. Brecher.

50 Prion Diseases: Marc L. Turner.

51 Pathogen Inactivation: Bjarte G. Solheim and Jerard Seghatchian.

Part III - Noninfectious Hazards.

52 Hemolytic Transfusion Reactions: Robertson D. Davenport.

53 Febrile, Allergic, and Nonimmune Transfusion Reactions: Gregory J. Pomper.

54 Transfusion-Associated Graft-vs-Host Disease: John E. Levine and James L. M. Ferrara.

55 Tranfusional Iron Overload: Sujit Sheth.

56 Transfusion-Related Acute Lung Injury: Jonathan P. Wallis and Ulrich J. H. Sachs.

Section V. Cell and Tissue Therapy.

57 HLA Antigens and Alleles: Thomas M. Williams.

58 Tissue Banking: Jeanne V. Linden, William F. Zaloga and A. Bradley Eisenbrey.

59 Adoptive Immunotherapy: Catherine M. Bollard and Helen Heslop.

60 Gene Therapy in Transfusion Medicine: Emanuela M. Bruscia and Diane S. Krause.

61 Tissue Engineering and Regenerative Medicine: Clay Quint and Laura Niklason.

Section VI. Delivery of Transfusion and Transplantation Services.

62 Recruitment and Screening of Donors and the Collection, Processing, and Testing of Blood: Kendall P Crookston, Susan L. Wilkinson and Toby L. Simon.

63 Current Legal Issues in Transfusion Medicine: Edward M. Mansfield, Thomas K. Berg, Kurt A. Leiheit, John Parker Sweeny and P. Robert Rigney.

64 Current Good Manufacturing Practice: P Ann Hoppe and Sheryl A. Kochman.

65 Transplant Organizations and Networks in the Regulation of Cellular Therapy Programs: Dennis L. Confer.

66 Hospital Transfusion Committee and Quality Assurance: Pamela Clark and Paul D. Mintz.


Companion PC and Mac Compatible CD-ROMs.

CD-ROM 1: All chapters of the book with a full text search function.

CD-ROM 2: Cases.

1 Posttransfusion Hemolysis: Marian Petrides and Nicole A. Pele.

2 Child with Low Fibrinogen: Marian Petrides and Donna Castellone.

3 Head Injury, Sudden Dyspnea: Marian Petrides.

4 A Transfusion Fatality: Marian Petrides.

5 Platelet Refractoriness: Marian Petrides.

6 An Unexpected Panagglutinin: Marian Petrides.

7 Postsurgical Bleeding: Marian Petrides.

8 Jehovah's Witness Surgery: Christopher P. Stowell and Marian Petrides.

9 Delayed Fever and Dark Urine: Marian Petrides.

10 Fever in Neutropenic Child: Marian Petrides and Dava S. Cleveland-Noriega

"It is an enjoyable book to read, as well as a very good reference too, not just for the transfusion lab and on haematologists' shelves, but also in general libraries." (Royal College of Pathologists, 1 April 2011)

 "The list of contributing authors includes some of the most well-known experts in different areas of transfusion medicine and its related areas.” (European Journal of Haematology, 2010)


"Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available." (Doody's Reviews, June 2009)

  • The most comprehensive and practical reference on transfusion science and medicine available.
  • Brand new chapters on the measurement of cell kinetics, obstetric transfusion practice, cord blood, transfusion alternatives, regenerative medicine
  • Includes a new co-editor - Bjarte G. Solheim from the University of Oslo, Norway
  • Contains 2 companion CDs containing interactive case studies and the complete text in searchable format