Russell, Hugo & Ayliffe's Principles and Practice of Disinfection, Preservation & Sterilization, 4th Edition
Part I begins with an historical overview, followed by descriptions of the types of antimicrobial agents, factors affecting efficacy, evaluation, modes of action and types of resistance. Also included is a new chapter on the problems of biofilms, as there are particular difficulties in inactivating sessile bacteria.
Part II covers topics relating to sterilization and the control of these processes, including heat, radiation, gases and filtration. It also includes updated material on new and emerging technologies, discusses special problems in hospitals, dentistry and pharmaceutical practices, and concludes with an evaluation of the activity of agents and good manufacturing. The section relating to the spoilage of wood, paper, textiles, paints and stonework in the preservation section has been removed to ensure that this edition is focused on issues relating specifically to health and medicine.
"This superb book is the best of its kind available and one that will undoubtedly be useful, if not essential, to workers in a variety of industries. Thirty-one distinguished specialists deal comprehensively with the subject matter indicated by the title ... The book is produced with care, is very readable with useful selected references at the end of each chapter and an excellent index. It is an essential source book for everyone interested in this field. For pharmacy undergraduates, it will complement the excellent text on pharmaceutical microbiology by two of the present editors."
The Pharmaceutical Journal
"This is an excellent book. It deals comprehensively and authoritatively with its subject with contributions from 31 distinguished specialists. There is a great deal to interest all those involved in hospital infection ... This book is exceptionally well laid out. There are well chosen references for each chapter and an excellent index. It is highly recommended." The Journal of Hospital Infection.
"The editors and authors must be congratulated for this excellent treatise on nonantibiotic antimicrobial measures in hospitals and industry ... The publication is highly recommended to hospital and research personnel, especially to clinical microbiologists, infection-control and environmental-safety specialists, pharmacists, and dieticians."
New England Journal of Medicine.
* Discusses increasing problems of natural and acquired resistance to antibiotics
* New contributors give a fresh approach to the subject and ensure international coverage
* Systematic review of sterilization methods, with uses and advantages outlined for each
* Evaluation of disinfectants and their mechanisms of action