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Schizophrenia, 2nd Edition

Schizophrenia, 2nd Edition

Steven R. Hirsch (Editor), Daniel R. Weinberger (Editor)

ISBN: 978-1-405-14010-2

Apr 2008, Wiley-Blackwell

768 pages

Select type: E-Book



Schizophrenia is one of the most complex and puzzling diseases to affect mankind. It is the most common of the severe mental illnesses (psychoses) with an estimated prevalence of 0.5 - 1% in the general population and accounts for a very large portion of the day to day workload of the average psychiatrist. 50% of long-term psychiatric patients in mental hospitals are schizophrenic.

There is a great deal of controversy about the causes, diagnosis and treatment of schizophrenia with the consequence that a huge amount of research is carried out in the field by psychiatrists, psychologists, neuroscientists and pharmacologists. For the average practising psychiatrist seeing schizophrenics on a regular basis, making sense of the vast body of information on the subject and filtering out what is of clinical relevance can be very difficult. There is a constant stream of new drugs emerging and the newer generation of drugs (the so-called atypicals) is very effective, but often expensive.

The Editors (one American and one British) are both highly respected clinical psychiatrists who are probably the leading experts on schizophrenia from their respective countries and jointly have published almost 150 papers on the subject.
They have brought together a strong group of contributors from the USA, UK and Europe to produce what will be an essential reference for the trainee and practising psychiatrist.

The book consists of four sections; descriptive aspects, causative aspects, physical treatments and psychological/behavioural/social treatments. There will be discussion of the theoretical controversies over symptomatology, classification and aetiology, the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. There will be chapters on organic models of schiziophrenia, neurodevelopmental, genetic and structural studies and the role of high-expressed emotion. The final section will cover social and environmental treatment, the role of the families of schizophrenics and the psychoanalytical therapies. There is a new chapter on the patient's perspective written by a former patient.



Preface to the Second Edition.

Preface to the First Edition.

Part 1: Descriptive Aspects.

Chapter 1: Concepts of Schizophrenia.

Chapter 2: Descriptive Psychopathology.

Chapter 3: Syndromes of Schizophrenia.

Chapter 4: Schizophrenia in Childhood.

Chapter 5: Atypical Psychotic Disorders.

Chapter 6: Late Life Schizophrenia.

Chapter 7: The Schizophrenia Spectrum Personality Disorders.

Chapter 8: Course and Outcome of Schizophrenia.

Chapter 9: Depression in Schizophrenia.

Chapter 10: Neurocognitive Deficits in Schizophrenia.

Part 2: Biological Aspects.

Chapter 11: The Secondary Schizophrenias.

Chapter 12: The Epidemiological Horizon.

Chapter 13: Factors Increasing the Risk for Schizophrenia.

Chapter 14: Genetics of Schizophrenia.

Chapter 15: Biology of Genetic Susceptibility.

Chapter 16: Electrophysiology.

Chapter 17: Neuropathology of Schizophrenia.

Chapter 18: Schizophrenia as a Neurodevelopmental Disorder.

Chapter 19: The Neurochemistry of Schizophrenia.

Chapter 20: The Dopamine Theory Revisited.

Chapter 21: Animal Neuropharmacology and its Predicition of Clinical Response.

Chapter 22: Brain Imaging.

Part 3: Physical Treatments.

Chapter 23: The Clinical Treatment of Schizophrenia with Antipsychotic edication.

Chapter 24: The Acute Treatment of Schizophrenia with Antipscyhotic Medication.

Chapter 25: Maintenance, Medication and Relapse Prevention.

Chapter 26: Treatment resistent Schizophrenia.

Chapter 27: Electroconvulsive Therapy in Schizophrenia.

Chapter 28: Neuroleptic-induced Acute Extrapyramidal Syndromes and Tardive Dyskinesia.

Chapter29: Non-neurological Side Effects of Antipsychotic Agents.

Part 4: Social, Environmental and Psychosocial Aspects.

Chapter 30: Violence and Schizophrenia.

Chapter 31: Schizophrenia and Psychosocial Stresses.

Chapter 32: Psychiatric Rehabilitation and the Application of Cognitive Behavioural Therapies.

Chapter 33: Psychological Treatments and Therapies for Schizophrenia.

Chapter 34: Community Care.

Chapter 35: Patient's Perspective of Schizophrenia.

Chapter 36: Economics of Schizophrenia and its Treatment.


Critical acclaim for the first edition

"...well-edited book could serve as a textbook for a course or a reference book for clinicians and researchers. It is a comprehensive update of mpressive index..."
New England Journal of Medicine

" excellent book drawing together a vast range of ought to be on the shelves of any jobbing psychiatrists..."
Psychological Medicine

" admirable source of authoritative yet judicious opinions...inexpensive gem."
British Journal of Psychiatry

* American and British editorship.

* Both editors are highly respected clinical psychiatrists - probably the leading experts on schizophrenia from their respective countries.

* An essential reference for the trainee and practising psychiatrist.

* New chapters including one on the patient's perspective, written by a former patient.