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Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals

Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals

Nissim Garti

ISBN: 978-0-470-28175-8

Oct 2012

396 pages

In Stock



This book will describe fundamentals and recent developments in the area of Self-Assembled Supramolecular Architecture and their relevance to the  understanding of the functionality of  membranes  as delivery systems for active ingredients. As the heirarchial architectures determine their performance capabilities, attention will be paid to theoretical and design aspects related to the construction of lyotropic liquid crystals: mesophases such as lamellar, hexagonal, cubic, sponge phase micellosomes. The book will bring to the reader mechanistic aspects, compositional considerations, transition within phases, solubilization capacities, drug entrapment and release mechanisms and transmembrane, transdermal, and other transport phenomena. It will stress the importance of these mesostructures to crystallization and polymorphism of drugs, fats, and nutraceuticals and will discuss regioselectivity of organic and enzymatic reactions that take place at interfaces and within the channels of the mesophase. The book will bring studies on the use of these mesophase as crystallization or particulation media for the formation of nanoparticles and nanocrystals. Chapters will discuss applications in the areas of pharmaceuticals, food, cosmetics, plastics, paper, agro-chemistry and industrial applications.

Preface vii

Contributors xi

1. Physics of Self-Assembly of Lyotropic Liquid Crystals 1
Raffaele Mezzenga

2. Rheological Theory and Simulation of Surfactant Nematic Liquid Crystals 21
Alejandro D. Rey and E. E. Herrera-Valencia

3. Dividing Planes of Hexagonal HII Mesophase 79
Vesselin Kolev, Abraham Aserin, and Nissim Garti

4. Nanocharacterization of Lyotropic Liquid Crystalline Systems 97
Patrick G. Hartley and Hsin-Hui Shen

5. Self-Assembly in Lipidic Particles 129
Anan Yaghmur and Otto Glatter

6. Hierarchically Organized Systems Based on Liquid Crystalline Phases 157
Chandrashekhar V. Kulkarni and Otto Glatter

7. Synthesis and Alignment of Nanostructured Materials Using Liquid Crystals 193
Idit Amar-Yuli, Abraham Aserin, and Nissim Garti

8. Recent Developments in Lyotropic Liquid Crystals as Drug Delivery Vehicles 219
Dima Libster, Abraham Aserin, and Nissim Garti

9. Stimuli-Responsive Lipid-Based Self-Assembled Systems 257
Ben J. Boyd and Wye-Khay Fong

10. Nonlamellar Lipid Liquid Crystalline Structures at Interfaces 289
Debby P. Chang and Tommy Nylander

11. Multicompartment Lipid Nanocarriers for Targeting of Cells Expressing Brain Receptors 319
Claire Géral, Angelina Angelova, Borislav Angelov, Valérie Nicolas, and Sylviane Lesieur

Index 357