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Standards of Mouse Model Phenotyping

Standards of Mouse Model Phenotyping

Martin Hrabé de Angelis (Editor), Pierre Chambon (Editor), Steve Brown (Editor)

ISBN: 978-3-527-60870-6

Sep 2009, Wiley-Blackwell

358 pages



This is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.
Generation of mouse models
Endocrinologic anomalies
Metabolic analysis
Neurologic disorders
Lung function
Nociceptive features
Eye disorders
Molecular phenotyping
Cardio-vascular disorders
Host-pathogen interactions