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Templated Organic Synthesis

Templated Organic Synthesis

François Diederich (Editor), Peter J. Stang (Editor)

ISBN: 978-3-527-61353-3

Jul 2008

431 pages

$152.99

Description

Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products.

The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.
TEMPLATES IN SUPRAMOLECULAR CHEMISTRY
Templates in Organic Synthesis: Definitions and Roles
Molecular Imprinting: Templated Materials for Recognition and Catalysis
Templated Synthesis of Catenanes and Rotaxanes
Templated Synthesis of Carcerands, Containers, and Capsules
Template-directed Nucleic Acid Synthesis
TEMPLATES IN ORGANIC SYNTHESIS
Tether-directed Remote Functionalization
Regio- and Stereoselective Multiple Functionalization of Fullerenes
Template-controlled Oligomerizations
Templated Ring-closing Reactions
Templated Stereoselective Synthesis Using Remote Covalent Tethers