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The Art of Process Chemistry

The Art of Process Chemistry

Nobuyoshi Yasuda (Editor)

ISBN: 978-3-527-63356-2

Nov 2010

298 pages


Providing must-have knowledge for the pharmaceutical industry and process chemists in industry, this ready reference offers solutions for saving time and money and supplying -- in a sustainable way -- valuable products. Application-oriented and well structured, each chapter presents successful strategies for the latest modern drugs, showing how to provide very fast bulk quantities of drug candidates. Throughout, the text illustrates how all the key factors are interwoven and dependent on one another in creating optimized methods for optimal products.

Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate

CCR5 Receptor Antagonist

5a-Reductase Inhibitors -
The Finasteride Story

Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist

SERM: Selective Estrogen Receptor Modulator

HIV Integrase Inhibitor: Raltegravir

Cyclopentane-Based NK1 Receptor Antagonist

Glucokinase Activator

CB1R Inverse Agonist -
"The book will be of great value to students looking to move into a career in process research; the enthusiasm and commitment of the authors comes over in the text, and the attention to detail and emphasis on mechanistic evaluation is a lesson to all. Academics will find much material that can be used in teaching . . . so in conclusion, this is an outstanding book which discusses the art of process research and developing process understanding." (Organic Process, Research & Development Journal, 17 December 2010)