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The Biology of Hyaluronan

The Biology of Hyaluronan

David Evered (Editor), Julie Whelan (Editor)

ISBN: 978-0-470-51377-4

Sep 2007

308 pages

Select type: O-Book


Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.
Partial table of contents:

Secondary Structures in Hyaluronan Solutions: Chemical and Biological Implications (J. Scott).

Turnover and Metabolism of Hyaluronan (J. Fraser & T. Laurent).

Enzymic Pathways of Hyaluronan Catabolism (L. Rodén, et al.).

Hyaluronan and Hyaluronan-Binding Proteins in Cartilaginous Tissues (R. Mason, et al.).

The Role of a Cell-Associated Hyaluronan-Binding Protein in Fibroblast Behavior (E. Turley).

The Role and Regulation of Tumor-Associated Hyaluronan (W. Knudson, et al.).

Interactions Between Cells of the Immune System and Hyaluronate Synthesis by Human Dermal Fibroblasts (T. Whiteside & R. Buckingham).

Hyaluronan and Angiogenesis (D. West & S. Kumar).

Changes in Hyaluronan Concentration in Tissues and Body Fluids in Disease States (A. Engström-Laurent).

The Specific Interaction Between Fibrin(ogen) and Hyaluronan: Possible Consequences in Hemostasis, Inflammation and Wound Healing (P. Weigel, et al.).

General Discussion.

Index of Contributors.

Subject Index.