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The Pyrazines, Supplement 1, Volume 58



The Pyrazines, Supplement 1, Volume 58

D. J. Brown (Editor)

ISBN: 978-0-471-46143-2 April 2003 576 Pages


This book serves as a supplement to The Pyrazines, Volume 41 of the Chemistry of Heterocyclic Compounds series. It covers the literature published between 1979 and 2000, and–together with Volume 41–provides a complete, up-to-date reference for heterocyclic chemists. It emphasizes practical approaches to pyrazine chemistry, offers a full appendix of all simple pyrazines up to 2000, and features detailed coverage of the following topics:
  • Systematic descriptions of all primary synthetic routes to pyrazines
  • Other preparative routes to alkylpyrazines and their reactions
  • Halogenopyrazines and their synthetic uses
  • Oxypyrazines and trivial names for pharmaceutical or agrochemical pyrazines
  • Thiopyrazines
  • Amino-, nitro-, and other similar pyrazines and their reactions
  • Pyrazinecarboxylic acids and their derivatives

The supplement features extensive cross-references to the original volume and uses chemical nomenclature as per current IUPAC recommendations

Chapter 1: Primary Syntheses From Aliphatic or Carbocyclic Synthons.

Chapter 2: Primary Syntheses from Other Heterocyclic Systems.

Chapter 3: Pyrazine, Alkylpyrazines, and Arylpyrazines.

Chapter 4: Halogenopyrazines.

Chapter 5: Oxypyrazines.

Chapter 6: Thiopyrazines.

Chapter 7: Nitro-, Amino-, and Related Pyrazines.

Chapter 8: Pyrazinecarboxylic Acids and Related Derivatives.

Appendix: Table of Simple Pyrazines.


"...embraces a mass of important historical material as well as a modern systematic treatment of pyrazine chemistry." (SciTech Book News, Vol. 26, No. 2, June 2002)