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The Way of Synthesis

Tomas Hudlicky, Josephine W. Reed

ISBN: 978-3-527-31444-7

Sep 2007

1018 pages

Select type: Paperback

In Stock

$119.00

Description

This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds.
With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry.

""I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication."" (Victor Snieckus)

Buy Both and Save 25%!

This item: The Way of Synthesis

Methods and Reagents for Green Chemistry: An Introduction (Hardcover $155.00)

Original Price:$274.00

Purchased together:$205.50

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INTRODUCTION
The History of Synthesis
Milestones in Organic Sythesis
STRATEGY AND TACTICS
Principles and Issues Impacting Synthesis (Strategy)
Principles and Issues Impacting Design (Strategy)
Principles and Issues of Methods (Tactics)
COMPARATIVE DESIGN: CLASSICS IN TERPENE SYNTHESIS
Juvenile Hormones
Cedrenes
Zizaanes
Hydroazulenes
Vernolepin
Triquinanes
Compactin
Aphidicolin
Miscellaneous Diterpenes
Taxol
COMPARATIVE DESIGN: CLASSICS IN ALKALOID SYNTHESIS
Lycopodium Alkaloids
Daphniphyllum Alkaloids, Daphnilactone A
Pyrrolizidine Alkaloids
Amaryllidaceae Alkaloids
Morphine
Indole Alkaloids
MISCELLANEOUS SYNTHESES
Maytansine
Palytoxin
Brevetoxin B
Indinavir
OUTLOOK
""Hudlick and Reed produced a fascinating read featuring numerous epigraphs, quotations, and personal remarks for synthetic chemists at all levels."" (CHOICE, February 2008)

""...The Way of Synthesis provides much information for its price.""  (Angewandte International Edition, December 2007)

  • Provides a historical view of the evolution of synthesis
  • Looks at principles and issues impacting synthesis and design as well as principles and issues of methods
  • Sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir
  • Presents not only synthetic ways to design organic compounds, it contains also a compilation of total synthesis with a COMPARATIVE view of multiple designs for the same target
  • Key parts, strategies and tactics are highlighted by a second color 
  • Concludes with a look at future perspectives and the personal recollections of chemists involved in the presented synthesis
  • Statement of one reviewer: ""WOW! It is an impressive tome. I also think there is as much between the lines as there is in the lines. Wonderful!""