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Thomas' Hematopoietic Cell Transplantation, 3rd Edition



Thomas' Hematopoietic Cell Transplantation, 3rd Edition

Karl G. Blume (Editor), Stephen J. Forman (Editor), Frederick R. Appelbaum (Editor)

ISBN: 978-1-405-14011-9 April 2008 Wiley-Blackwell 1600 Pages


NEW - the leading book in its field now fully updated and revised!

Click here to access two FREE sample chapters!

An Essential resource for all hematologists, oncologists, pathologists, pediatricians, immunologists and all others interested in this dynamic area of medicine!

Why you should buy this book....

  • Extensive coverage of subject area - from the scientific basis to the view of the future
  • Includes all experimental research and clinical application
  • Combined the knowledge and expertise of over 170 international specialists
  • Clear structure and layout
  • Over 500 illustrations, including a colour plate section

Why buy the NEW edition......

  • New and fully revised to reflect the latest developments in this fast moving field
  • 10 new chapters, covering some of the latest developments - see below for the complete tables of content
Scientific Basis for Hematopoietic Cell Transplantation.

1 A History of Bone Marrow Transplantation, 3.

E. Donnall Thomas.

2 Uses and Growth of Hematopoietic Cell Transplantation, 9.

Mary M. Horowitz.

3 Overview of Hematopoietic Cell Transplantation Immunology, 16.

Paul J. Martin.

4 Histocompatibility, 31.

Eric Mickelson & Effie W. Petersdorf.

5 Functional Evolution of the Major Histocompatibility Complex, 43.

Lakshmi K. Gaur.

6 The Hematopoietic Microenvironment, 53.

Claudio Brunstein & Catherine M. Verfaillie.

7 Molecular Aspects of Stem Cell Renewal, 62.

Peter M. Lansdorp.

8 Biology of Hematopoietic Stem and Progenitor Cells, 69.

Markus G. Manz, Koichi Akashi & Irving L. Weissman.

9 Expansion of Hematopoietic Stem Cells, 96.

Colleen Delaney, Robert Andrews & Irwin Bernstein.

10 Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells, 107.

Thomas Moritz & David A. Williams.

11 Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells, 118.

Donald B. Kohn & Gay M. Crooks.

12 Pharmacological Basis for High-Dose Chemotherapy, 130.

James H. Doroshow & Timothy Synold.

13 Preparative Regimens and Modification of Regimen-Related Toxicities, 158.

William I. Bensinger & Ricardo Spielberger.

14 Radiotherapeutic Principles of Hematopoietic Cell Transplantation, 178.

Brenda Shank & Richard T. Hoppe.

15 Radioimmunotherapy and Hematopoietic Cell Transplantation, 198.

Dana C. Matthews & Frederick R. Appelbaum.

16 Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation, 209.

Nelson J. Chao.

17 T-Cell Depletion to Prevent Graft-vs.-Host Disease, 221.

Robert J. Soiffer.

18 Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation, 234.

Eileen Bryant & Paul J. Martin.

19 Antibody Mediated Purging, 244.

John G. Gribben.

20 Pharmacologic Purging of Bone Marrow, 254.

O. Michael Colvin.

21 Molecular Inhibition of Gene Expression in Hematopoietic Cells, 258.

Joanna B. Opalinska & Alan M. Gewirtz.

22 The Detection and Significance of Minimal Residual Disease, 272.

Jerald P. Radich & Marilyn L. Slovak.

23 Pathology of Hematopoietic Cell Transplantation, 286.

George E. Sale, Howard M. Shulman & Robert C. Hackman.

24 Mechanisms of Tolerance, 300.

Megan Sykes.

25 The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases, 324.

Judith A. Shizuru.

26 Murine Models for Graft-vs.-Host Disease, 344.

Robert Korngold & Thea M. Friedman.

27 The Pathophysiology of Graft-vs.-Host Disease, 353.

James L.M. Ferrara & Joseph Antin.

28 Graft-versus-Tumor Responses, 369.

Alexander Fefer.

29 Adoptive Immunotherapy with Antigen-Specific T Cells, 380.

Stanley R. Riddell & Philip D. Greenberg.

30 Autologous Graft-vs.-Host Disease, 405.

Allan D. Hess & Richard J. Jones.

31 Biostatistical Methods in Hematopoietic Cell Transplantation, 414.

Joyce C. Niland.

32 Outcomes Research in Hematopoietic Cell Transplantation, 434.

Stephanie J. Lee.

Patient-Related Issues in Hematopoietic Cell Transplantation.

33 The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation, 449.

Karl G. Blume & Michael D. Amylon.

34 Clinical and Administrative Support for Hematopoietic Cell Transplant Programs, 463.

Laura L. Adams & Angela A. Johns.

35 Nursing Issues in Hematopoietic Cell Transplantation, 469.

Rosemary C. Ford, Judy Campbell & Juanita Madison.

36 The Patient’s Perspective, 483.

Susan K. Stewart.

37 Ethical Issues in Hematopoietic Cell Transplantation, 488.

David S. Snyder.

38 Psychosocial Issues in Hematopoietic Cell Transplantation, 497.

Michael A. Andrykowski & Richard P. McQuellon.

39 Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients, 507.

Karen Syrjala.

40 Sexuality after Hematopoietic Cell Transplantation, 519.

D. Kathryn Tierney.

Sources of Hematopoietic Cells for Human Transplant.

41 Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation, 531.

Phyllis I. Warkentin, Lewis Nick & Elizabeth J. Shpall.

42 Hematopoietic Cell Donors, 538.

Dennis L. Confer.

43 Cord Blood Hematopoietic Cell Transplantation, 550.

Hal E. Broxmeyer & Franklin O. Smith.

44 In Utero Transplantation, 565.

Alan W. Flake & Esmail D. Zanjani.

45 Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy, 576.

Judith Ng-Cashin & Thomas Shea.

46 Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation, 588.

Norbert Schmitz.

47 Cryopreservation of Hematopoietic Cells, 599.

Scott D. Rowley.

48 Recombinant Growth Factors after Hematopoietic Cell Transplantation, 613.

Jürgen Finke & Roland Mertelsmann.

49 Hematopoietic Cell Donor Registries, 624.

Jeffrey W. Chell.

Complications and Their Management.

50 Graft-vs.-Host Disease, 635.

Keith M. Sullivan.

51 Bacterial Infections, 665.

John R. Wingard & Helen L. Leather.

52 Fungal Infections after Hematopoietic Cell Transplantation, 683.

Janice (Wes) M. Y. Brown.

53 Cytomegalovirus Infection, 701.

John A. Zaia.

54 Herpes Simplex Virus Infections, 727.

James I. Ito.

55 Varicella-Zoster Virus Infections, 732.

Ann M. Arvin.

56 Epstein-Barr Virus Infection, 749.

Richard F. Ambinder.

57 Other Viral Infections after Hematopoietic Cell Transplantation, 757.

Michael Boeckh.

58 Gastrointestinal and Hepatic Complications, 769.

Simone I. Strasser & George B. McDonald.

59 Neurological Complications of Hematopoietic Cell Transplantation, 811.

Harry Openshaw.

60 Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation, 824.

Margaret R. O’Donnell.

61 Principles of Transfusion Support before and after Hematopoietic Cell Transplantation, 833.

Jeffrey McCullough.

62 Immunological Reconstitution following Hematopoietic Cell Transplantation, 853.

Robertson Parkman & Kenneth I. Weinberg.

63 Vaccination of Hematopoietic Cell Transplant Recipients, 862.

Clare A. Dykewicz.

64 Pulmonary Complications after Hematopoietic Cell Transplantation, 873.

David A. Horak.

65 Nutritional Support of Hematopoietic Cell Recipients, 883.

Sally Weisdorf-Schindele & Sarah Jane Schwarzenberg.

66 Pain Management, 894.

Jonathan R. Gavrin & F. Peter Buckley.

67 Oral Complications, 911.

Mark M. Schubert, Douglas E. Peterson & Michele E. Lloid.

68 Growth and Development after Hematopoietic Cell Transplantation, 929.

Jean E. Sanders.

69 Delayed Complications after Hematopoietic Cell Transplantation, 944.

Mary E.D. Flowers & H. Joachim Deeg.

70 Secondary Malignancies after Hematopoietic Cell Transplantation, 962.

Smita Bhatia & Ravi Bhatia.

Allogeneic Transplantation for Acquired Diseases.

71 Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia, 981.

George E. Georges & Rainer Storb.

72 Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria, 1002.

Robert P. Witherspoon.

73 Allogeneic Transplantation for Chronic Myeloid Leukemia, 1007.

Frederick R. Appelbaum.

74 Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia, 1018.

Robert A. Krance.

75 Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia, 1025.

Keith E. Stockerl-Goldstein & Karl G. Blume.

76 Allogeneic Transplantation for Acute Myeloid Leukemia in Children, 1040.

David A. Margolis & James T. Casper.

77 Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults, 1055.

Stephen J. Forman.

78 Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children, 1067.

Stella M. Davies, Norma K.C. Ramsay & John H. Kersey.

79 Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders, 1084.

Jeanne E. Anderson.

80 Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma, 1096.

David G. Maloney & Gösta Gahrton.

81 Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia, 1105.

Issa Khouri & Richard Champlin.

82 Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors, 1116.

Claudio Anasetti & Andrea Velardi.

83 Hematopoietic Cell Transplantation from Unrelated Donors, 1132.

Effie W. Petersdorf.

84 Management of Relapse after Allogeneic Transplantation, 1150.

Robert H. Collins, Jr.

85 Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders, 1164.

Brenda M. Sandmaier & Rainer Storb.

86 Allogeneic Hematopoietic Cell Transplantation for Solid Tumors, 1177.

Richard W. Childs & Ramaprasad Srinivasan.

Autologous Transplantation for Acquired Diseases.

87 Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin’s Disease, 1191.

Philip J. Bierman & Auayporn Nademanee.

88 Autologous Hematopoietic Cell Transplantation for Non-Hodgkin’s Lymphoma, 1207.

Sandra J. Horning & James O. Armitage.

89 Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia, 1221.

Anthony S. Stein & Stephen J. Forman.

90 Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia, 1238.

Charles A. Linker.

91 Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia, 1250.

Ravi Bhatia & Philip B. McGlave.

92 Autologous Hematopoietic Cell Transplantation for Multiple Myeloma, 1262.

Laurence Catley & Kenneth Anderson.

93 Autologous Hematopoietic Cell Transplantation for AL Amyloidosis, 1283.

Raymond L. Comenzo & Morie A. Gertz.

94 Hematopoietic Cell Transplantation for Breast Cancer, 1298.

Karen H. Antman.

95 Hematopoietic Cell Transplantation in Germ Cell Tumors, 1308.

Brandon Hayes-Lattin & Craig R. Nichols.

96 Hematopoietic Cell Transplantation in Ovarian Carcinoma, 1320.

Patrick J. Stiff.

97 Hematopoietic Cell Transplantation for Neuroblastoma, 1333.

Katherine K. Matthay.

98 Hematopoietic Cell Transplantation for Brain Tumors, 1345.

Ira J. Dunkel & Jonathan L. Finlay.

99 Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors, 1354.

Allen R. Chen & Curt I. Civin.

100 AIDS and Hematopoietic Transplantation: HIV Infection, AIDS, Lymphoma and Gene Therapy, 1369.

John A. Zaia, J. Scott Cairns & John J. Rossi.

101 Hematopoietic Stem Cell Transplantation for Autoimmune Diseases, 1385.

Alan Tyndall & Alois Gratwohl.

102 Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation, 1394.

Robert S. Negrin.

Allogeneic Transplantation for Inherited Disease.

103 Marrow Transplantation in Thalassemia, 1409.

Guido Lucarelli & Reginald A. Clift.

104 Hematopoietic Cell Transplantation for Sickle Cell Disease, 1417.

Mark C. Walters.

105 Hematopoietic Cell Transplantation for Immunodeficiency Diseases, 1430.

Trudy N. Small, Wilhelm Friedrich & Richard J. O’Reilly.

106 Hematopoietic Cell Transplantation for Osteopetrosis, 1443.

Peter F. Coccia.

107 Hematopoietic Cell Transplantation for Storage Diseases, 1455.

Charles Peters.

108 Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders, 1471.

Rajni Agarwal.

109 Hematopoietic Cell Transplantation for Fanconi Anemia, 1483.

John E. Wagner, Margaret L. MacMillan & Arleen D. Auerbach.

The Future.

110 Hematopoietic Cell Transplantation in the 21st Century, 1507.

Ernest Beutler.

Colorplates, facing page 296.

Robert C. Hackman.


Index, 1511

"A must for the bookshelf of any person who has even the vaguest interest in the biology or practice of marrow, blood, or umbilical-cord hematopoietic stem-cell transplantation."

New England Journal of Medicine

"Essential addition to the library of any unit performing bone marrow transplants."

Journal of Hematotherapy

"Uniformly informative, helpful, well-organised and presented, comprehensive, up-to-date and well-referenced."

British Journal of Haematology

"Overwhelmingly complete, extremely up-to-date and each chapter is written by a world leader in the field."

Clinical and Laboratory Haematology