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Handbook of Metalloproteins

Albrecht Messerschmidt, Max Planck Institut, Martinsried
Robert Huber, Max Planck Institut, Martinsried
Karl Wieghardt, Max Planck Institut Mulheim an der Ruhr
Thomas Poulos, Univ. of California at Irvine

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ISBN: 0-471-62743-7
Pages: 1248 
Publication Date: June 2001


In recent years, the analysis and classification of metalloenzymes and metalloproteins at the interface between chemistry and biology has accelerated. Many developments and initiatives have taken place, particularly due to progress in x-ray and NMR studies. 

Presented in a large format and full colour this two-volume handbook provides a comprehensive, yet focused, collection of 105 metalloproteins. It covers the most relevant transition metals in the field: Iron, Nickel, Copper, Cobalt, Molybdenum, Manganese Tungsten and Vanadium. 

Providing detailed information on the well-known metalloproteins, each compound has a computer-modelled structure included. Additional information on the sequence information, synthesis and spectroscopic properties, functional aspects as well as key chemical, biological, physical and medical properties of the compound is described. 

This title is an essential reference source for researchers in the area and will be of great use to inorganic and bioinorganic chemists, as well as biochemists, crystallographers and biospectroscopists. The Handbook of Metalloproteins is the first comprehensive handbook to cover the major metalloproteins, and it includes:

  • Comparative information and extensive referencing to current literature 
  • Contributions from over two hundred internationally renowned re-searchers such as Douglas Rees, Charles Stout, Stephen Lippard as well as Nobel Prize winner Robert Huber 
  • Structural and functional data presented in an organized manner and incorporates full-color representation of molecular structures throughout
  • Complete information from molecular biology, enzymology, spectroscopy, biochemistry, chemistry, biophysics, macromolecular crystallography and structural biology 
  • Comprehensive sections covering: 
    • Functional Class, Occurrence, Amino Acid Sequence Information, Protein Production, Purification and Molecular Characterization, Metal Content and Cofactors, Activity Test, Spectroscopy, 3D Structure, Functional Aspects 

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